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Recombinant Human CLEC4M protein, His & T7-tagged

Cat.No. : CLEC4M-1855H
Product Overview : Recombinant Human CLEC4M aa. (Pro242~Glu399 (Accession # Q9H2X3)) fused with N-terminal His & T7 tag was produced in E. coli cells.
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  • Gene Information
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Source : E. coli
Species : Human
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 22.3kDa
Protein length : Pro242~Glu399 (Accession # Q9H2X3)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 6.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : CLEC4M C-type lectin domain family 4 member M [ Homo sapiens (human) ]
Official Symbol : CLEC4M
Synonyms : CLEC4M; C-type lectin domain family 4 member M; CD299; LSIGN; CD209L; L-SIGN; DCSIGNR; HP10347; DC-SIGN2; DC-SIGNR; C-type lectin domain family 4 member M; CD209 antigen-like protein 1; CD299 antigen; DC-SIGN-related protein; dendritic cell-specific ICAM-3-grabbing non-integrin 2; liver/lymph node-specific ICAM-3 grabbing non-integrin; mannose binding C-type lectin DC-SIGNR
Gene ID : 10332
mRNA Refseq : NM_001144905.1
Protein Refseq : NP_001138377.1
UniProt ID : Q9H2X3

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there any diseases or conditions associated with CLEC4M dysfunction? 12/02/2021

Research suggests that CLEC4M may be involved in the pathogenesis of certain viral infections, as well as in modulating immune responses in conditions such as HIV and hepatitis.

What are the potential clinical applications of CLEC4M in the context of viral infections? 12/13/2020

CLEC4M could potentially be targeted for the development of antiviral therapies or vaccines, as its role in recognizing and responding to viral pathogens is of great interest to researchers.

What are the implications of CLEC4M in the field of vaccine development? 04/27/2019

CLEC4M's role in recognizing viral pathogens makes it an interesting target for vaccine development, as it may be involved in eliciting immune responses against specific viruses.

How does CLEC4M contribute to the immune response in the context of fungal infections? 07/04/2018

CLEC4M has been shown to recognize and bind to specific carbohydrates present on the surface of certain fungi, contributing to immune responses against fungal pathogens.

How does CLEC4M function in the context of viral infections? 02/24/2016

CLEC4M binds to viral glycoproteins, facilitating the uptake of viruses into dendritic cells and promoting antiviral immune responses.

Customer Reviews (3)

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Reviews
04/13/2021

    Its outstanding performance, coupled with its ease of use, has enhanced the overall efficiency and accuracy of my research.

    07/28/2018

      I highly recommend the CLEC4M Protein to researchers seeking a reliable and high-performing protein for their ELISA assays and protein electron microscopy structure analysis.

      07/04/2018

        The CLEC4M Protein has greatly contributed to the success of my experiments, providing reliable and robust data.

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