Recombinant Human CSF1R protein (aa 543-922), His-GST-tagged
Cat.No. : | CSF1R-1970H |
Product Overview : | Recombinant Human CSF1R (NP_005202.2) protein (Lys 543-Asp 922) is produced by Baculovirus-Insect Cells expression system. This protein is fused with a His-GST tag at the N-terminal. |
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Source : | Baculovirus-Insect Cells |
Species : | Human |
Tag : | His&GST |
Predicted N Terminal : | Met |
Form : | Supplied as sterile 50mM Tris, 100mM NaCl, 20% gly, 0.3mM DTT, pH 8.0. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Molecular Mass : | The recombinant human CSF1R (aa 543-922) /GST chimera consists of 617 amino acids and has a calculated molecular mass of 71 KDa. It migrates as an approximately 60 KDa band in SDS-PAGE under reducing conditions. |
Protein length : | Lys 543-Asp 922 |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 82 % as determined by SDS-PAGE |
Stability : | Samples are stable for up to twelve months from date of receipt at -70 centigrade. |
Storage : | Store it under sterile conditions at -20 centigrade to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles |
Shipping : | Kinases are highly recommended to be shipped at frozen temperature with blue ice or dry ice. Shipment made at ambient temperature may seriously affect the activity of the ordered products. |
Gene Name : | CSF1R colony stimulating factor 1 receptor [ Homo sapiens ] |
Official Symbol : | CSF1R |
Synonyms : | CSF1R; colony stimulating factor 1 receptor; C FMS; CD115; CSFR; CSF-1-R; CD115 antigen; FMS; FIM2; HDLS; C-FMS; CSF-1R; M-CSF-R; |
Gene ID : | 1436 |
mRNA Refseq : | NM_005211 |
Protein Refseq : | NP_005202 |
MIM : | 164770 |
UniProt ID : | P07333 |
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Not For Human Consumption!
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Customer Reviews (3)
Write a reviewWith its remarkable quality, reliability, and the manufacturer's excellent technical support, I am confident that it will be an invaluable asset in driving my scientific inquiries forward and facilitating groundbreaking discoveries in my field.
This variety allows me to select the most appropriate option based on the specific requirements of my research.
the manufacturer's commitment to quality control and rigorous testing guarantees the reliability and reproducibility of the CSF1R protein, which is essential for obtaining accurate and consistent results.
Q&As (5)
Ask a questionYes, drugs like pexidartinib have been approved for the treatment of certain rare tumors called tenosynovial giant cell tumors (TGCT) that overexpress CSF1R.
CSF1R inhibitors can modulate the tumor microenvironment by reducing the number of tumor-associated macrophages and promoting an anti-tumor immune response.
Yes, CSF1R inhibitors are often used in combination with chemotherapy and immunotherapy to enhance treatment effectiveness.
CSF1R inhibitors are being investigated for cancer therapy to block tumor-promoting macrophages and slow down cancer progression.
Research is ongoing, and CSF1R inhibitors are being explored as a potential therapy for neurodegenerative diseases, but no FDA-approved treatments currently exist.
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