Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human CYR61 Protein, GST-tagged

Cat.No. : CYR61-2295H
Product Overview : Human CYR61 full-length ORF ( AAH01271.1, 1 a.a. - 381 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : The secreted protein encoded by this gene is growth factor-inducible and promotes the adhesion of endothelial cells. The encoded protein interacts with several integrins and with heparan sulfate proteoglycan. This protein also plays a role in cell proliferation, differentiation, angiogenesis, apoptosis, and extracellular matrix formation. [provided by RefSeq, Sep 2011]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 67.65 kDa
AA Sequence : MSSRIARALALVVTLLHLTRLAPST CPAACHCPLEAPKCAPGVGLVRDGC GCCKVCAKQLNEDCSKTQPCDHTKG LECNFGASSTALKGICRAQSEGRPC EYNSRIYQNGESFQPNCKHQCTCID GAVGCIPLCPQELSLPNLGCPNPRL VKVTGQCCEEWVCDEDSIKDPMEDQ DGLLGKELGFDASEVELTRNNELIA VGKGSSLKRLPVFGMEPRILYNPLQ GQKCIVQTTSWSQCSKTCGTGISTR VTNDNPECRLVKETRICKVRPCGQP VYSSLKKGKKCSKTKKSPEPVRFTY AGCLSVKKYRPKYCGSCVDGRCCTP QLTRTVKMRFRCEDGETFSKNVMMI QSCKCNYNCPHANEAAFPFYRLFND IHKFRD
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : CYR61 cysteine-rich, angiogenic inducer, 61 [ Homo sapiens ]
Official Symbol : CYR61
Synonyms : CYR61; cysteine-rich, angiogenic inducer, 61; IGFBP10; protein CYR61; CCN1; GIG1; IBP-10; IGFBP-10; CCN family member 1; IGF-binding protein 10; cysteine-rich, anigogenic inducer, 61; cysteine-rich heparin-binding protein 61; insulin-like growth factor-binding protein 10;
Gene ID : 3491
mRNA Refseq : NM_001554
Protein Refseq : NP_001545
MIM : 602369
UniProt ID : O00622

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (6)

Ask a question
What did recent research on CYR61 find? 10/09/2021

Recent studies have found that CYR61 plays an important role in tumor development and metastasis, especially in cancers such as non-small cell lung cancer, breast cancer, gastric cancer, and colorectal cancer.

Which drugs can inhibit the expression level of CYR61? 03/03/2021

There are currently no drugs specifically targeting CYR61, but some anti-tumor drugs can inhibit the expression level of CYR61, such as chemotherapy drugs and targeted therapy drugs.

What is the relationship between the level of CYR61 expression and patient survival? 02/08/2021

Studies have shown that high levels of CYR61 expression are associated with decreased patient survival, suggesting that it may be used as a biomarker to predict patient survival.

What signaling pathways is CYR61 involved in? 12/26/2020

CYR61 is involved in a variety of signaling pathways, including Wnt, MAPK, ERK, and PI3K.

What is the significance of regulating the expression level of CYR61 for the treatment of diseases? 06/03/2020

Regulating the expression level of CYR61 is of great significance for the treatment of diseases, especially for the treatment of cancer, and can slow down the growth and spread of tumors by inhibiting the expression level of CYR61.

How can the relationship between CYR61 expression levels and disease risk be assessed? 02/24/2020

The relationship between CYR61 expression levels and disease risk can be assessed by immunohistochemistry or western blot analysis of the patient's tissue samples.

Customer Reviews (3)

Write a review
Reviews
07/18/2022

    It has good effect and stability in gene expression regulation.

    06/04/2022

      Will not interact with other drugs, will not affect.

      07/20/2021

        The application performance is stable in common colorimetric reactions.

        Ask a Question for All CYR61 Products

        Required fields are marked with *

        My Review for All CYR61 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends