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Recombinant Human DDB2 Protein, GST-tagged

Cat.No. : DDB2-057H
Product Overview : Recombinant Human full length DDB2 ( NP_000098.1, 1 a.a. - 427 a.a.) protein was expressed in wheat germ with GST tag.
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  • Gene Information
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Description : This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities.
Source : Wheat Germ
Species : Human
Tag : GST
Form : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Molecular Mass : 74.3 kDa
AA Sequence : MAPKKRPETQKTSEIVLRPRNKRSR SPLELEPEAKKLCAKGSGPSRRCDS DCLWVGLAGPQILPPCRSIVRTLHQ HKLGRASWPSVQQGLQQSFLHTLDS YRILQKAAPFDRRATSLAWHPTHPS TVAVGSKGGDIMLWNFGIKDKPTFI KGIGAGGSITGLKFNPLNTNQFYAS SMEGTTRLQDFKGNILRVFASSDTI NIWFCSLDVSASSRMVVTGDNVGNV ILLNMDGKELWNLRMHKKKVTHVAL NPCCDWFLATASVDQTVKIWDLRQV RGKASFLYSLPHRHPVNAACFSPDG ARLLTTDQKSEIRVYSASQWDCPLG LIPHPHRHFQHLTPIKAAWHPRYNL IVVGRYPDPNFKSCTPYELRTIDVF DGNSGKMMCQLYDPESSGISSLNEF NPMGDTLASAMGYHILIWSQEEART RK
Storage : Store at -80 centigrade.
Gene Name : DDB2 damage-specific DNA binding protein 2, 48kDa [ Homo sapiens ]
Official Symbol : DDB2
Synonyms : DDB2; damage-specific DNA binding protein 2, 48kDa; damage specific DNA binding protein 2 (48kD); DNA damage-binding protein 2; DDB p48 subunit; DDBB; FLJ34321; UV damaged DNA binding protein 2; UV DDB2; xeroderma pigmentosum group E protein; UV-DDB 2; UV-damaged DNA-binding protein 2; damage-specific DNA-binding protein 2; UV-DDB2
Gene ID : 1643
mRNA Refseq : NM_000107
Protein Refseq : NP_000098
MIM : 600811
UniProt ID : Q92466

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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