Recombinant Human DKK3 Protein, GST-tagged

• Cat.No.: DKK3-2667H
• Product Overview: Human DKK3 full-length ORF ( AAH07660.1, 1 a.a. - 350 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 64.7 kDa
• AA Sequence: MQRLGATLLCLLLAAAVPTAPAPAP TATSAPVKPGPALSYPQEEATLNEM FREVEELMEDTQHKLRSAVEEMEAE EAAAKASSEVNLANLPPSYHNETNT DTKVGNNTIHVHREIHKITNNQTGQ MVFSETVITSVGDEEGRRSHECIID EDCGPSMYCQFASFQYTCQPCRGQR MLCTRDSECCGDQLCVWGHCTKMAT RGSNGTICDNQRDCQPGLCCAFQRG LLFPVCTPLPVEGELCHDPASRLLD LITWELEPDGALDRCPCASGLLCQP HSHSLVYVCKPTFVGSRDQDGEILL PREVPDEYEVGSFMEEVRQELEDLE RSLTEEMALGEPAAAAAALLGGEEI
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DKK3 dickkopf 3 homolog (Xenopus laevis) [ Homo sapiens ]
• Official Symbol: DKK3
• Synonyms: DKK3; dickkopf 3 homolog (Xenopus laevis); dickkopf (Xenopus laevis) homolog 3; dickkopf-related protein 3; regulated in glioma; REIC; RIG; dkk-3; hDkk-3; dickkopf-3; RIG-like 5-6; RIG-like 7-1; dickkopf homolog 3
• Gene ID: 27122
• mRNA Refseq: NM_001018057
• Protein Refseq: NP_001018067
• MIM: 605416
• UniProt ID: Q9UBP4