| Description : |
The DPP4 gene encodes dipeptidyl peptidase 4, which is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic type II transmembrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. Dipeptidyl peptidase 4 is highly involved in glucose and insulin metabolism, as well as in immune regulation. This protein was shown to be a functional receptor for Middle East respiratory syndrome coronavirus (MERS-CoV), and protein modeling suggests that it may play a similar role with SARS-CoV-2, the virus responsible for COVID-19. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Fc |
| Form : |
Lyophilized |
| Molecular Mass : |
112 kDa |
| Protein Length : |
766 |
| AA Sequence : |
MKTPWKVLLGLLGAAALVTIITVPV VLLNKGTDDATADSRKTYTLTDYLK NTYRLKLYSLRWISDHEYLYKQENN ILVFNAEYGNSSVFLENSTFDEFGH SINDYSISPDGQFILLEYNYVKQWR HSYTASYDIYDLNKRQLITEERIPN NTQWVTWSPVGHKLAYVWNNDIYVK IEPNLPSYRITWTGKEDIIYNGITD WVYEEEVFSAYSALWWSPNGTFLAY AQFNDTEVPLIEYSFYSDESLQYPK TVRVPYPKAGAVNPTVKFFVVNTDS LSSVTNATSIQITAPASMLIGDHYL CDVTWATQERISLQWLRRIQNYSVM DICDYDESSGRWNCLVARQHIEMST TGWVGRFRPSEPHFTLDGNSFYKII SNEEGYRHICYFQIDKKDCTFITKG TWEVIGIEALTSDYLYYISNEYKGM PGGRNLYKIQLSDYTKVTCLSCELN PERCQYYSVSFSKEAKYYQLRCSGP GLPLYTLHSSVNDKGLRVLEDNSAL DKMLQNVQMPSKKLDFIILNETKFW YQMILPPHFDKSKKYPLLLDVYAGP CSQKADTVFRLNWATYLASTENIIV ASFDGRGSGYQGDKIMHAINRRLGT FEVEDQIEAARQFSKMGFVDNKRIA IWGWSYGGYVTSMVLGSGSGVFKCG IAVAPVSRWEYYDSVYTERYMGLPT PEDNLDHYRNSTVMSRAENFKQVEY LLIHGTADDNVHFQQSAQISKALVD VGVDFQAMWYTDEDHGIASSTAHQH IYTHMSHFIKQCFSLP |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
