Recombinant Human DUSP14, T7 -tagged

• Cat.No.: DUSP14-28072TH
• Product Overview: Recombinant full length protein (Human): DUSP14 with T7 tag at N-terminus.

Specification

• Description: Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP14 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al.
• Conjugation: T7
• Source: E. coli
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: 0.002% Sodium AzideConstituents: 10mM Tris, 10mM DTT, 0.1% Triton X-100, pH 8
• Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
• Sequence Similarities: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.Contains 1 tyrosine-protein phosphatase domain.

Gene Information

• Gene Name: DUSP14 dual specificity phosphatase 14 [ Homo sapiens ]
• Official Symbol: DUSP14
• Synonyms: DUSP14; dual specificity phosphatase 14; dual specificity protein phosphatase 14; MKP 1 like protein tyrosine phosphatase; MKP L; MKP6
• Gene ID: 11072
• mRNA Refseq: NM_007026
• Protein Refseq: NP_008957
• MIM: 606618
• Uniprot ID: O95147
• Chromosome Location: 17q12
• Pathway: Hypertrophy Model, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, conserved biosystem
• Function: MAP kinase tyrosine/serine/threonine phosphatase activity; hydrolase activity; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity