Recombinant Human EFEMP1 Protein, GST-tagged

• Cat.No.: EFEMP1-3085H
• Product Overview: Human EFEMP1 full-length ORF ( AAH14410, 1 a.a. - 493 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the encoded protein contains tandemly repeated epidermal growth factor-like repeats followed by a C-terminus fibulin-type domain. This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy. Alternatively spliced transcript variants that encode the same protein have been described.[provided by RefSeq, Nov 2009]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 79.97 kDa
• AA Sequence: MLKALFLTMLTLALVKSQDTEETIT YTQCTDGYEWDPVGQQCKDIDECDI VPDACKGGMKCVNHYGGYLCLPKTA QIIVNNEQPQQETQPAEGTSGATTG VVAASSMATSGVLPGGGFVASAAAV AGPEMQTGRNNFVIRRNPADPQRIP SNPSHRIQCAAGYEQSEHNVCQDID ECTAGTHNCRADQVCINLRGSFACQ CPPGYQKRGEQCVDIDECTIPPYCH QRCVNTPGSFYCQCSPGFQLAANNY TCVDINECDASNQCAQQCYNILGSF ICQCNQGYELSSDRLNCEDIDECRT SSYLCQYQCVNEPGKFSCMCPQGYQ VVRSRTCQDINECETTNECREDEMC WNYHGGFRCYPRNPCQDPYILTPEN RCVCPVSNAMCRELPQSIVYKYMSI RSDRSVPSDIFQIQATTIYANTINT FRIKSGSENGEFYLRQTSPVSAMLV LVKSLSGPREHIVDLEMLTASSIGT FRTSSVLRLTIIVGPFSF
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 [ Homo sapiens ]
• Official Symbol: EFEMP1
• Synonyms: EFEMP1; EGF containing fibulin-like extracellular matrix protein 1; DHRD, EGF containing fibulin like extracellular matrix protein 1 , FBNL, fibrillin like; EGF-containing fibulin-like extracellular matrix protein 1; FBLN3; fibulin 3; MTLV; S1 5; FIBL-3; fibulin-3; extracellular protein S1-5; DHRD; DRAD; FBNL; MLVT; S1-5; FLJ35535; MGC111353
• Gene ID: 2202
• mRNA Refseq: NM_001039348
• Protein Refseq: NP_001034437
• MIM: 601548
• UniProt ID: Q12805