Recombinant Full Length Human EFEMP1 Protein, C-Flag-tagged

• Cat.No.: EFEMP1-54HFL
• Product Overview: Recombinant Full Length Human EFEMP1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the encoded protein contains tandemly repeated epidermal growth factor-like repeats followed by a C-terminus fibulin-type domain. This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy. Alternatively spliced transcript variants that encode the same protein have been described.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 52.7 kDa
• AA Sequence: MLKALFLTMLTLALVKSQDTEETIT YTQCTDGYEWDPVRQQCKDIDECDI VPDACKGGMKCVNHYGGYLC LPKTAQIIVNNEQPQQETQPAEGTS GATTGVVAASSMATSGVLPGGGFVA SAAAVAGPEMQTGRNNFVIR RNPADPQRIPSNPSHRIQCAAGYEQ SEHNVCQDIDECTAGTHNCRADQVC INLRGSFACQCPPGYQKRGE QCVDIDECTIPPYCHQRCVNTPGSF YCQCSPGFQLAANNYTCVDINECDA SNQCAQQCYNILGSFICQCN QGYELSSDRLNCEDIDECRTSSYLC QYQCVNEPGKFSCMCPQGYQVVRSR TCQDINECETTNECREDEMC WNYHGGFRCYPRNPCQDPYILTPEN RCVCPVSNAMCRELPQSIVYKYMSI RSDRSVPSDIFQIQATTIYA NTINTFRIKSGNENGEFYLRQTSPV SAMLVLVKSLSGPREHIVDLEMLTV SSIGTFRTSSVLRLTIIVGP
  FSFTRTRPLEQKLISEEDLAANDIL DYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Secreted Protein

Gene Information

• Gene Name: EFEMP1 EGF containing fibulin extracellular matrix protein 1 [ Homo sapiens (human) ]
• Official Symbol: EFEMP1
• Synonyms: DHRD; DRAD; FBNL; MLVT; MTLV; S1-5; FBLN3; FIBL-3
• Gene ID: 2202
• mRNA Refseq: NM_001039348.3
• Protein Refseq: NP_001034437.1
• MIM: 601548
• UniProt ID: Q12805