Recombinant Human EFEMP1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: EFEMP1-5614H
• Product Overview: EFEMP1 MS Standard C13 and N15-labeled recombinant protein (NP_001034437) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the encoded protein contains tandemly repeated epidermal growth factor-like repeats followed by a C-terminus fibulin-type domain. This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy. Alternatively spliced transcript variants that encode the same protein have been described.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 54.6 kDa
• AA Sequence: MLKALFLTMLTLALVKSQDTEETIT YTQCTDGYEWDPVRQQCKDIDECDI VPDACKGGMKCVNHYGGYLCLPKTA QIIVNNEQPQQETQPAEGTSGATTG VVAASSMATSGVLPGGGFVASAAAV AGPEMQTGRNNFVIRRNPADPQRIP SNPSHRIQCAAGYEQSEHNVCQDID ECTAGTHNCRADQVCINLRGSFACQ CPPGYQKRGEQCVDIDECTIPPYCH QRCVNTPGSFYCQCSPGFQLAANNY TCVDINECDASNQCAQQCYNILGSF ICQCNQGYELSSDRLNCEDIDECRT SSYLCQYQCVNEPGKFSCMCPQGYQ VVRSRTCQDINECETTNECREDEMC WNYHGGFRCYPRNPCQDPYILTPEN RCVCPVSNAMCRELPQSIVYKYMSI RSDRSVPSDIFQIQATTIYANTINT FRIKSGNENGEFYLRQTSPVSAMLV LVKSLSGPREHIVDLEMLTVSSIGT FRTSSVLRLTIIVGPFSFTRTRPLE QKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 [ Homo sapiens (human) ]
• Official Symbol: EFEMP1
• Synonyms: EFEMP1; EGF containing fibulin-like extracellular matrix protein 1; DHRD, EGF containing fibulin like extracellular matrix protein 1, FBNL, fibrillin like; EGF-containing fibulin-like extracellular matrix protein 1; FBLN3; fibulin 3; MTLV; S1 5; FIBL-3; fibulin-3; extracellular protein S1-5; DHRD; DRAD; FBNL; MLVT; S1-5; FLJ35535; MGC111353
• Gene ID: 2202
• mRNA Refseq: NM_001039348
• Protein Refseq: NP_001034437
• MIM: 601548
• UniProt ID: Q12805