Recombinant Human EFNB2 Protein, GST-tagged

• Cat.No.: EFNB2-3104H
• Product Overview: Human EFNB2 full-length ORF ( NP_004084.1, 1 a.a. - 333 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 63.3 kDa
• AA Sequence: MAVRRDSVWKYCWGVLMVLCRTAIS KSIVLEPIYWNSSNSKFLPGQGLVL YPQIGDKLDIICPKVDSKTVGQYEY YKVYMVDKDQADRCTIKKENTPLLN CAKPDQDIKFTIKFQEFSPNLWGLE FQKNKDYYIISTSNGSLEGLDNQEG GVCQTRAMKILMKVGQDASSAGSTR NKDPTRRPELEAGTNGRSSTTSPFV KPNPGSSTDGNSAGHSGNNILGSEV ALFAGIASGCIIFIVIIITLVVLLL KYRRRHRKHSPQHTTTLSLSTLATP KRSGNNNGSEPSDIIIPLRTADSVF CPHYEKVSGDYGHPVYIVQEMPPQS PANIYYKV
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: EFNB2 ephrin-B2 [ Homo sapiens ]
• Official Symbol: EFNB2
• Synonyms: EFNB2; ephrin-B2; EPLG5; eph related receptor tyrosine kinase ligand 5; HTK ligand; Htk L; HTKL; LERK5; ligand of eph related kinase 5; MGC126226; MGC126227; MGC126228; LERK-5; ligand of eph-related kinase 5; eph-related receptor tyrosine kinase ligand 5; Htk-L
• Gene ID: 1948
• mRNA Refseq: NM_004093
• Protein Refseq: NP_004084
• MIM: 600527
• UniProt ID: P52799

Reviews

01/05/2022

During the experiment, the technician helped me solve the problems in a timely and accurate manner.

01/02/2022

The EFNB2 proteins purchased from your company is suitable for WB.

01/23/2021

Received high quality protein products and obtained satisfactory experimental results.

Q&As

What effect does EphB6 overexpression have on EFNB2?

EphB6 overexpression up-regulates the expression of its ligand EFNB2.

What diseases is EFNB2 involved in?

EFNB2 is associated with breast, colon, bladder, cervical and other cancers.

What is the biological function of EFNB2?

EFNB2 is involved in tissue plasticity, tumorigenesis, and other biological processes.

Where is EFNB2 mainly expressed?

EFNB2 is widely expressed in tumor vasculature.

What is the association between EFNB2 and BUC cells?

EFNB2 promotes BUC cell proliferation by inhibiting apoptosis in BUC cells.

How is EphB6 related to EFNB2?

EFNB2 is one of the physiological ligands of EphB6 that functions by binding to EphB6.