Recombinant Human FBXO3 Protein (1-471 aa), His-tagged
Cat.No. : | FBXO3-1731H |
Product Overview : | Recombinant Human FBXO3 Protein (1-471 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Cell Biology. Protein Description: Full Length. |
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- Gene Information
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Description : | Substrate recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation. |
Source : | Yeast |
Species : | Human |
Tag : | His |
Form : | Tris-based buffer,50% glycerol |
Molecular Mass : | 56.6 kDa |
Protein length : | 1-471 aa |
AA Sequence : | MAAMETETAPLTLESLPTDPLLLIL SFLDYRDLINCCYVSRRLSQLSSHD PLWRRHCKKYWLISEEEKTQKNQCW KSLFIDTYSDVGRYIDHYAAIKKAW DDLKKYLEPRCPRMVLSLKEGAREE DLDAVEAQIGCKLPDDYRCSYRIHN GQKLVVPGLLGSMALSNHYRSEDLL DVDTAAGGFQQRQGLKYCLPLTFCI HTGLSQYIAVEAAEGRNKNEVFYQC PDQMARNPAAIDMFIIGATFTDWFT SYVKNVVSGGFPIIRDQIFRYVHDP ECVATTGDITVSVSTSFLPELSSVH PPHYFFTYRIRIEMSKDALPEKACQ LDSRYWRITNAKGDVEEVQGPGVVG EFPIISPGRVYEYTSCTTFSTTSGY MEGYYTFHFLYFKDKIFNVAIPRFH MACPTFRVSIARLEMGPDEYEEMEE EEEEEEEEDEDDDSADMDESDEDDE EERRRRVFDVPIRRRRCSRLF |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA with reconstitution instruction is sent along with the products. |
Gene Name : | FBXO3 F-box protein 3 [ Homo sapiens ] |
Official Symbol : | FBXO3 |
Synonyms : | FBXO3; F-box protein 3; FBA; FBX3; DKFZp564B092; |
Gene ID : | 26273 |
mRNA Refseq : | NM_012175 |
Protein Refseq : | NP_036307 |
MIM : | 609089 |
UniProt ID : | Q9UK99 |
Products Types
◆ Recombinant Protein | ||
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FBXO3-897H | Recombinant Human FBXO3 Protein, His (Fc)-Avi-tagged | +Inquiry |
FBXO3-1949R | Recombinant Rat FBXO3 Protein, His (Fc)-Avi-tagged | +Inquiry |
FBXO3-3929H | Recombinant Human FBXO3 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
FBXO3-6300HCL | Recombinant Human FBXO3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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