Recombinant Human FTH1 Protein, GST-tagged

• Cat.No.: FTH1-4531H
• Product Overview: Human FTH1 full-length ORF ( AAH11359, 1 a.a. - 183 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 45.87 kDa
• AA Sequence: MTTASTSQVRQNYHQDSEAAINRQI NQELYASYVYLSMSYYFDRDDVALK NFAKYFLHQSHEEREHAEKLMKLQN QRGGRIFLQDIKKPDCDDWESGLNA MECALHLEKNVNQSLLELHKLATDK NDPHLCDFIETHYLNEQVKAIKELG DHVTNLRKMGAPESGLAEYLFDKHT LGDSDNES
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FTH1 ferritin, heavy polypeptide 1 [ Homo sapiens ]
• Official Symbol: FTH1
• Synonyms: FTH1; ferritin, heavy polypeptide 1; FTHL6; ferritin heavy chain; apoferritin; FHC; FTH; PIG15; placenta immunoregulatory factor; PLIF; proliferation inducing protein 15; ferritin H subunit; proliferation-inducing protein 15; cell proliferation-inducing gene 15 protein; MGC104426
• Gene ID: 2495
• mRNA Refseq: NM_002032
• Protein Refseq: NP_002023
• MIM: 134770
• UniProt ID: P02794