Recombinant Human GLB1 Protein, GST-tagged
Cat.No. : | GLB1-4945H |
Product Overview : | Human GLB1 full-length ORF ( AAH07493, 1 a.a. - 677 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes beta-galactosidase-1, a lysosomal enzyme that hydrolyzes the terminal beta-galactose from ganglioside substrates and other glycoconjugates. Defects in this gene are the cause of GM1-gangliosidosis and Morquio B syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 100.21 kDa |
AA Sequence : | MPGFLVRILLLLLVLLLLGPTRGLR NATQRMFEIDYSRDSFLKDGQPFRY ISGSIHYSRVPRFYWKDRLLKMKMA GLNAIQTYVPWNFHEPWPGQYQFSE DHDVEYFLRLAHELGLLVILRPGPY ICAEWEMGGLPAWLLEKESILLRSS DPDYLAAVDKWLGVLLPKMKPLLYQ NGGPVITVQVENEYGSYFACDFDYL RFLQKRFRHHLGDDVVLFTTDGAHK TFLKCGALQGLYTTVDFGTGSNITD AFLSQRKCEPKGPLINSEFYTGWLD HWGQPHSTIKTEAVASSLYDILARG ASVNLYMFIGGTNFAYWNGANSPYA AQPTSYDYDAPLSEAGDLTEKYFAL RNIIQKFEKVPEGPIPPSTPKFAYG KVTLEKLKTVGAALDILCPSGPIKS LYPLTFIQVKQHYGFVLYRTTLPQD CSNPAPLSSPLNGVHDRAYVAVDGI PQGVLERNNVITLNITGKAGATLDL LVENMGRVNYGAYINDFKGLVSNLT LSSNILTDWTIFPLDTEDAVRSHLG GWGHRDSGHHDEAWAHNSSNYTLPA FYMGNFSIPSGIPDLPQDTFIQFPG WTKGQVWINGFNLGRYWPARGPQLT LFVPQHILMTSAPNTITVLELEWAP CSSDDPELCAVTFVDRPVIGSSVTY DHPSKPVEKRLMPPPPQKNKDSWLD HV |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | GLB1 galactosidase, beta 1 [ Homo sapiens ] |
Official Symbol : | GLB1 |
Synonyms : | GLB1; galactosidase, beta 1; elastin receptor 1 (67kD), elastin receptor 1, 67kDa, ELNR1; beta-galactosidase; EBP; lactase; acid beta-galactosidase; elastin receptor 1, 67kDa; ELNR1; MPS4B; |
Gene ID : | 2720 |
mRNA Refseq : | NM_000404 |
Protein Refseq : | NP_000395 |
MIM : | 611458 |
UniProt ID : | P16278 |
Products Types
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◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionGLB1 deficiency can lead to neurodegeneration, causing progressive deterioration of the nervous system.
There are three subtypes: GM1 gangliosidosis, mucopolysaccharidosis IVB, and combined GM1 gangliosidosis and mucopolysaccharidosis IVB.
While dietary interventions may help manage certain symptoms, they do not address the underlying cause of the deficiency.
Symptoms may include developmental delay, skeletal abnormalities, vision and hearing loss, and neurological deterioration.
Yes, prenatal testing through genetic analysis of amniotic fluid or chorionic villus sampling can detect GLB1 deficiency.
Customer Reviews (3)
Write a reviewTheir support has been invaluable in troubleshooting and providing efficient solutions, enhancing the overall efficiency and productivity of my experiments.
Its versatility allows for exploring its various roles and functions, shedding light on its significance in crucial biochemical pathways and cellular processes.
Their knowledgeable and responsive team has consistently demonstrated their ability to address any concerns or challenges I have encountered along the way.
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