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Recombinant Human GLB1 Protein, GST-tagged

Cat.No. : GLB1-4945H
Product Overview : Human GLB1 full-length ORF ( AAH07493, 1 a.a. - 677 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes beta-galactosidase-1, a lysosomal enzyme that hydrolyzes the terminal beta-galactose from ganglioside substrates and other glycoconjugates. Defects in this gene are the cause of GM1-gangliosidosis and Morquio B syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 100.21 kDa
AA Sequence : MPGFLVRILLLLLVLLLLGPTRGLR NATQRMFEIDYSRDSFLKDGQPFRY ISGSIHYSRVPRFYWKDRLLKMKMA GLNAIQTYVPWNFHEPWPGQYQFSE DHDVEYFLRLAHELGLLVILRPGPY ICAEWEMGGLPAWLLEKESILLRSS DPDYLAAVDKWLGVLLPKMKPLLYQ NGGPVITVQVENEYGSYFACDFDYL RFLQKRFRHHLGDDVVLFTTDGAHK TFLKCGALQGLYTTVDFGTGSNITD AFLSQRKCEPKGPLINSEFYTGWLD HWGQPHSTIKTEAVASSLYDILARG ASVNLYMFIGGTNFAYWNGANSPYA AQPTSYDYDAPLSEAGDLTEKYFAL RNIIQKFEKVPEGPIPPSTPKFAYG KVTLEKLKTVGAALDILCPSGPIKS LYPLTFIQVKQHYGFVLYRTTLPQD CSNPAPLSSPLNGVHDRAYVAVDGI PQGVLERNNVITLNITGKAGATLDL LVENMGRVNYGAYINDFKGLVSNLT LSSNILTDWTIFPLDTEDAVRSHLG GWGHRDSGHHDEAWAHNSSNYTLPA FYMGNFSIPSGIPDLPQDTFIQFPG WTKGQVWINGFNLGRYWPARGPQLT LFVPQHILMTSAPNTITVLELEWAP CSSDDPELCAVTFVDRPVIGSSVTY DHPSKPVEKRLMPPPPQKNKDSWLD HV
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : GLB1 galactosidase, beta 1 [ Homo sapiens ]
Official Symbol : GLB1
Synonyms : GLB1; galactosidase, beta 1; elastin receptor 1 (67kD), elastin receptor 1, 67kDa, ELNR1; beta-galactosidase; EBP; lactase; acid beta-galactosidase; elastin receptor 1, 67kDa; ELNR1; MPS4B;
Gene ID : 2720
mRNA Refseq : NM_000404
Protein Refseq : NP_000395
MIM : 611458
UniProt ID : P16278

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does GLB1 protein deficiency impact the nervous system? 07/04/2022

GLB1 deficiency can lead to neurodegeneration, causing progressive deterioration of the nervous system.

What are the different subtypes of GLB1 deficiency? 02/15/2020

There are three subtypes: GM1 gangliosidosis, mucopolysaccharidosis IVB, and combined GM1 gangliosidosis and mucopolysaccharidosis IVB.

Can GLB1 deficiency be managed through dietary interventions? 12/11/2019

While dietary interventions may help manage certain symptoms, they do not address the underlying cause of the deficiency.

What are the symptoms of GLB1 deficiency? 08/29/2018

Symptoms may include developmental delay, skeletal abnormalities, vision and hearing loss, and neurological deterioration.

Can GLB1 deficiency be detected prenatally? 05/21/2016

Yes, prenatal testing through genetic analysis of amniotic fluid or chorionic villus sampling can detect GLB1 deficiency.

Customer Reviews (3)

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12/10/2021

    Their support has been invaluable in troubleshooting and providing efficient solutions, enhancing the overall efficiency and productivity of my experiments.

    04/03/2019

      Its versatility allows for exploring its various roles and functions, shedding light on its significance in crucial biochemical pathways and cellular processes.

      05/16/2016

        Their knowledgeable and responsive team has consistently demonstrated their ability to address any concerns or challenges I have encountered along the way.

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