Recombinant Mouse Glb1 Protein, His-tagged
Cat.No. : | Glb1-181M |
Product Overview : | Recombinant Mouse Glb1(Ser192~Pro432) fused with His tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a preproprotein that is proteolytically cleaved to yield a signal peptide and a proproptein that is subsequently processed to generate the active mature peptide. The encoded protein is a lysosomal enzyme that catalyzes the hydrolysis of terminal beta-D-galactose residues in various substrates like lactose, ganglioside GM1 and other glycoproteins. Mutations in the human gene are associated with GM1-gangliosidosis and Morquio B syndrome. Disruption of the mouse gene mirrors the symptoms of human gangliosidosis. Alternative splicing results in multiple transcript variants. |
Source : | E. coli |
Species : | Mouse |
Tag : | His |
Form : | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
Molecular Mass : | 28.8kDa |
Identity : | Reconstitute in PBS or others |
Protein length : | Ser192~Pro432 |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | > 95% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. If bio-activity of the protein is needed, please check active protein |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Reconstitution : | Reconstitute in PBS or others |
Gene Name : | Glb1 galactosidase, beta 1 [ Mus musculus ] |
Official Symbol : | Glb1 |
Synonyms : | GLB1; galactosidase, beta 1; beta-galactosidase; lactase; acid beta-galactosidase; beta-galactosidase complex; beta-galactosidase temporal; beta-galactosidase electrophoretic; beta-galactosidase systemic regulator; Bge; Bgl; Bgs; Bgt; Bgl-e; Bgl-s; Bgl-t; AW125515; C130097A14Rik; |
Gene ID : | 12091 |
mRNA Refseq : | NM_009752 |
Protein Refseq : | NP_033882 |
UniProt ID : | P23780 |
Products Types
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GLB1-3587M | Recombinant Mouse GLB1 Protein, His (Fc)-Avi-tagged | +Inquiry |
GLB1-984H | Recombinant Human GLB1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Gp9-183R | Recombinant Rat Gp9 Protein, His/GST-tagged | +Inquiry |
◆ Lysates | ||
GLB1-5910HCL | Recombinant Human GLB1 293 Cell Lysate | +Inquiry |
GLB1-5909HCL | Recombinant Human GLB1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionGLB1 deficiency can lead to neurodegeneration, causing progressive deterioration of the nervous system.
There are three subtypes: GM1 gangliosidosis, mucopolysaccharidosis IVB, and combined GM1 gangliosidosis and mucopolysaccharidosis IVB.
While dietary interventions may help manage certain symptoms, they do not address the underlying cause of the deficiency.
Symptoms may include developmental delay, skeletal abnormalities, vision and hearing loss, and neurological deterioration.
Yes, prenatal testing through genetic analysis of amniotic fluid or chorionic villus sampling can detect GLB1 deficiency.
Customer Reviews (3)
Write a reviewTheir support has been invaluable in troubleshooting and providing efficient solutions, enhancing the overall efficiency and productivity of my experiments.
Its versatility allows for exploring its various roles and functions, shedding light on its significance in crucial biochemical pathways and cellular processes.
Their knowledgeable and responsive team has consistently demonstrated their ability to address any concerns or challenges I have encountered along the way.
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