Recombinant Human GLRX Protein

• Cat.No.: GLRX-154H
• Product Overview: Recombinant Human GLRX Protein

Specification

• Description: This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.
• Species: Human
• Form: Lyophilized
• Stability: ≥ 1 year
• Storage: At -80 centigrade.
• Concentration: Concentration of glutaredoxin before lyophilization was 15.6 mg/mL.
• Storage Buffer: Lyophilized from 50 mM potassium phosphate, 0.1 mM EDTA, and 80 mM sodium chloride, pH 6.8
• Reconstitution: Reconstitute with water or buffer (300 μL will give 70 μM Grx1).

Gene Information

• Gene Name: GLRX glutaredoxin [ Homo sapiens (human) ]
• Official Symbol: GLRX
• Synonyms: GLRX; glutaredoxin; GRX; GRX1; glutaredoxin-1; TTase-1; thioltransferase; thioltransferase-1; EC 1.8.4.1
• Gene ID: 2745
• mRNA Refseq: NM_002064
• Protein Refseq: NP_002055
• MIM: 600443
• UniProt ID: P35754