Recombinant Human GM2A
Cat.No. : | GM2A-27454TH |
Product Overview : | Recombinant full length Human GM2A with N terminal proprietary tag. Predicted MW 47.3 kDa |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants. |
Protein length : | 193 amino acids |
Molecular Weight : | 47.300kDa inclusive of tags |
Source : | Wheat germ |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MQSLMQAPLLIALGLLLAAPAQAHLKKPSQLSSFSWDNCD EGKDPAVIRSLTLEPDPIIVPGNVTLSVMGSTSVPLSSPL KVDLVLEKEVAGLWIKIPCTDYIGSCTFEHFCDVLDMLIP TGEPCPEPLRTYGLPCHCPFKEGTYSLPKSEFVVPDLELP SWLTTGNYRIESVLSSSGKRLGCIKIAASLKGI |
Gene Name : | GM2A GM2 ganglioside activator [ Homo sapiens ] |
Official Symbol : | GM2A |
Synonyms : | GM2A; GM2 ganglioside activator; GM2 ganglioside activator protein; ganglioside GM2 activator; cerebroside sulfate activator protein; SAP 3; sphingolipid activator protein 3; |
Gene ID : | 2760 |
mRNA Refseq : | NM_000405 |
Protein Refseq : | NP_000396 |
MIM : | 613109 |
Uniprot ID : | P17900 |
Chromosome Location : | 5q33.1 |
Pathway : | Lysosome, organism-specific biosystem; Lysosome, conserved biosystem; |
Function : | beta-N-acetylhexosaminidase activity; sphingolipid activator protein activity; |
Products Types
◆ Recombinant Protein | ||
GM2A-993H | Recombinant Human GM2A Protein, His (Fc)-Avi-tagged | +Inquiry |
GM2A-299C | Recombinant Cynomolgus Monkey GM2A Protein, His (Fc)-Avi-tagged | +Inquiry |
GM2A-128H | Recombinant Human GM2A Protein (Met1-Ile193), C-His tagged, Animal-free, Carrier-free | +Inquiry |
Gm2a-3241M | Recombinant Mouse Gm2a Protein, Myc/DDK-tagged | +Inquiry |
GM2A-5001H | Recombinant Human GM2A Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
GM2A-450HCL | Recombinant Human GM2A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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