| Description : |
The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
His |
| Form : |
Lyophilized |
| Molecular Mass : |
24.5 kDa |
| Protein Length : |
319 |
| AA Sequence : |
MVGKMWPVLWTLCAVRVTVDAISVE TPQDVLRASQGKSVTLPCTYHTSTS SREGLIQWDKLLLTHTERVVIWPFS NKNYIHGELYKNRVSISNNAEQSDA SITIDQLTMADNGTYECSVSLMSDL EGNTKSRVRLLVLVPPSKPECGIEG ETIIGNNIQLTCQSKEGSPTPQYSW KRYNILNQEQPLAQPASGQPVSLKN ISTDTSGYYICTSSNEEGTQFCNIT VAVRSPSMNVALYVGIAVGVVAALI IIGIIIYCCCCRGKDDNTEDKEDAR PNREAYEEPPEQLRELSREREEEDD YRQEEQRSTGRESPDHLDQ |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
