Recombinant Human GPD1 Protein, GST-tagged

• Cat.No.: GPD1-5151H
• Product Overview: Human GPD1 full-length ORF ( AAH32234, 1 a.a. - 349 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 64.13 kDa
• AA Sequence: MASKKVCIVGSGNWGSAIAKIVGGN AAQLAQFDPRVTMWVFEEDIGGKKL TEIINTQHENVKYLPGHKLPPNVVA VPDVVQAAEDADILIFVVPHQFIGK ICDQLKGHLKANATGISLIKGVDEG PNGLKLISEVIGERLGIPMSVLMGA NIASEVADEKFCETTIGCKDPAQGQ LLKELMQTPNFRITVVQEVDTVEIC GTLKNVVAVGAGFCDGLGFGDNTKA AVIRLGLMEMIAFAKLFCSGPVSSA TFLESCGVADLITTCYGGRNRKVAE AFARTGKSIEQLEKELLNGQKLQGP ETARELYSILQHKGLVDKFPLFMAV YKVCYEGQPVGEFIHCLQNHPEHM
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) [ Homo sapiens ]
• Official Symbol: GPD1
• Synonyms: GPD1; glycerol-3-phosphate dehydrogenase 1 (soluble); glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic; glycerophosphate dehydrogenase; glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic; GPD-C; HTGTI; GPDH-C; FLJ26652
• Gene ID: 2819
• mRNA Refseq: NM_001257199
• Protein Refseq: NP_001244128
• MIM: 138420
• UniProt ID: P21695