Recombinant Human GRIN1 Protein

• Cat.No.: GRIN1-5343H
• Product Overview: Human GRIN1 full-length ORF (AAI56098.1) recombinant protein without tag.

Specification

• Description: The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Form: Liquid
• Molecular Mass: 103.2 kDa
• AA Sequence: MSTMRLLTLALLFSCSVARAACDPK IVNIGAVLSTRKHEQMFREAVNQAN KRHGSWKIQLNATSVTHKPNAIQMA LSVCEDLISSQVYAILVSHPPTPND HFTPTPVSYTAGFYRIPVLGLTTRM SIYSDKSIHLSFLRTVPPYSHQSSV WFEMMRVYSWNHIILLVSDDHEGRA AQKRLETLLEERESKAEKVLQFDPG TKNVTALLMEAKELEARVIILSASE DDAATVYRAAAMLNMTGSGYVWLVG EREISGNALRYAPDGILGLQLINGK NESAHISDAVGVVAQAVHELLEKEN ITDPPRGCVGNTNIWKTGPLFKRVL MSSKYADGVTGRVEFNEDGDRKFAN YSIMNLQNRKLVQVGIYNGTHVIPN DRKIIWPGGETEKPRGYQMSTRLKI VTIHQEPFVYVKPTLSDGTCKEEFT VNGDPVKKVICTGPNDTSPGSPRHT VPQCCYGFCIDLLIKLARTMNFTYE VHLVADGKFGTQERVNNSNKKEWNG MMGELLSGQADMIVAPLTINNERAQ YIEFSKPFKYQGLTILVKKEIPRST LDSFMQPFQSTLWLLVGLSVHVVAV MLYLLDRFSPFGRFKVNSEEEEEDA LTLSSAMWFSWGVLLNSGIGEGAPR SFSARILGMVWAGFAMIIVASYTAN LAAFLVLDRPEERITGINDPRLRNP SDKFIYATVKQSSVDIYFRRQVELS TMYRHMEKHNYESAAEAIQAVRDNK LHAFIWDSAVLEFEASQKCDLVTTG ELFFRSGFGIGMRKDSPWKQNVSLS ILKSHENGFMEDLDKTWVRYQECDS RSNAPATLTFENMAGVFMLVAGGIV AGIFLIFIEIAYKRHKDARRKQMQL AFAAVNVWRKNLQDRKSGRAEPDPK KKATFRAITSTLASSFKRRRSSKDT STGGGRGALQNQKDTVLPRRAIERE EGQLQLCSRHRES
• Applications: Antibody Production
  Functional Study
  Compound Screening
• Usage: Heating may cause protein aggregation. Please do not heat this product before electrophoresis.
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 25 mM Tris-HCl of pH8.0 containing 2% glycerol.

Gene Information

• Gene Name: GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 [ Homo sapiens ]
• Official Symbol: GRIN1
• Synonyms: GRIN1; glutamate receptor, ionotropic, N-methyl D-aspartate 1; NMDAR1; glutamate [NMDA] receptor subunit zeta-1; GluN1; NMD-R1; glutamate [NMDA] receptor subunit zeta 1; N-methyl-D-aspartate receptor subunit NR1; N-methyl-D-aspartate receptor channel, subunit zeta-1; NR1; MRD8; NMDA1
• Gene ID: 2902
• mRNA Refseq: NM_000832
• Protein Refseq: NP_000823
• MIM: 138249
• UniProt ID: Q05586