| Description : |
The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
99.31 kDa |
| AA Sequence : |
MSTMRLLTLALLFSCSVARAACDPK IVNIGAVLSTRKHEQMFREAVNQAN KRHGSWKIQLNATSVTHKPNAIQMA LSVCEDLISSQVYAILVSHPPTPND HFTPTPVSYTAGFYRIPVLGLTTRM SIYSDKSIHLSFLRTVPPYSHQSSV WFEMMRVYSWNHIILLVSDDHEGRA AQKRLETLLEERESKAEKVLQFDPG TKNVTALLMEAKELEARVIILSASE DDAATVYRAAAMLNMTGSGYVWLVG EREISGNALRYAPDGILGLQLINGK NESAHISDAVGVVAQAVHELLEKEN ITDPPRGCVGNTNIWKTGPLFKRVL MSSKYADGVTGRVEFNEDGDRKFAN YSIMNLQNRKLVQVGIYNGTHVIPN DRKIIWPGGETEKPRGYQMSTRLKI VTIHQEPFVYVKPTLSDGTCKEEFT VNGDPVKKVICTGPNDTSPGSPRHT VPQCCYGFCIDLLIKLARTMNFTYE VHLVADGKFGTQERVNNSNKKEWNG MMGELLSGQADMIVAPLTINNERAQ YIEFSKPFKYQGLTILVKKEIPRST LDSFMQPFQSTLWLLVGLSVHVVAV MLYLLDRFSPFGRFKVNSEEEEEDA LTLSSAMWFSWGVLLNSGIGEGAPR SFSARILGMVWAGFAMIIVASYTAN LAAFLVLDRPEERITGINDPRLRNP SDKFIYATVKQSSVDIYFRRQVELS TMYRHMEKHNYESAAEAIQAVRDNK LHAFIWDSAVLEFEASQKCDLVTTG ELFFRSGFGIGMRKDSPWKQNVSLS ILKSHENGFMEDLDKTWVRYQECDS RSNAPATLTFENMAGVFMLVAGGIV AGIFLIFIEIAYKRHKDARRKQMQL AFAAVNVWRKNLQQYHPTDITGPLN LSDPSVSTVVTRTRPLEQKLISEED LAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
