Recombinant Human GZMK Protein, GST-tagged

• Cat.No.: GZMK-4524H
• Product Overview: Human GZMK full-length ORF ( NP_002095.1, 1 a.a. - 264 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface nonself antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 55.3 kDa
• AA Sequence: MTKFSSFSLFFLIVGAYMTHVCFNM EIIGGKEVSPHSRPFMASIQYGGHH VCGGVLIDPQWVLTAAHCQYRFTKG QSPTVVLGAHSLSKNEASKQTLEIK KFIPFSRVTSDPQSNDIMLVKLQTA AKLNKHVKMLHIRSKTSLRSGTKCK VTGWGATDPDSLRPSDTLREVTVTV LSRKLCNSQSYYNGDPFITKDMVCA GDAKGQKDSCKGDSGGPLICKGVFH AIVSGGHECGVATKPGIYTLLTKKY QTWIKSNLVPPHTN
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GZMK granzyme K (granzyme 3; tryptase II) [ Homo sapiens ]
• Official Symbol: GZMK
• Synonyms: GZMK; granzyme K (granzyme 3; tryptase II); granzyme K (serine protease, granzyme 3; tryptase II); granzyme K; PRSS; TRYP2; NK-Tryp-2; granzyme 3; granzyme-3; tryptase II; fragmentin-3; NK-tryptase-2; granzyme K (serine protease, granzyme 3; tryptase II)
• Gene ID: 3003
• mRNA Refseq: NM_002104
• Protein Refseq: NP_002095
• MIM: 600784
• UniProt ID: P49863