Recombinant Human GZMM Protein, GST-tagged

• Cat.No.: GZMM-4526H
• Product Overview: Human GZMM full-length ORF ( AAH25701.1, 1 a.a. - 257 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and Met-ase, also known as granzyme M. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 54.01 kDa
• AA Sequence: MEACVSSLLVLALGALSVGSSFGTQ IIGGREVIPHSRPYMASLQRNGSHL CGGVLVHPKWVLTAAHCLAQRMAQL RLVLGLHTLDSPGLTFHIKAAIQHP RYKPVPALENDLALLQLDGKVKPSR TIRPLALPSKRQVVAAGTRCSMAGW GLTHQGGRLSRVLRELDLQVLDTRM CNNSRFWNGSLSPSMVCLAADSKDQ APCKGDSGGPLVCGKGRVLAGVLSF SSRVCTDIFKPPVATAVAPYVSWIR KVTGRSA
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GZMM granzyme M (lymphocyte met-ase 1) [ Homo sapiens ]
• Official Symbol: GZMM
• Synonyms: GZMM; granzyme M (lymphocyte met-ase 1); granzyme M; LMET1; lymphocyte met ase 1; MET1; met-ase; HU-Met-1; lymphocyte met-ase 1; Met-1 serine protease; natural killer cell granular protease
• Gene ID: 3004
• mRNA Refseq: NM_005317
• Protein Refseq: NP_005308
• MIM: 600311
• UniProt ID: P51124