Recombinant Human HSD3B2 Protein, GST-tagged
Cat.No. : | HSD3B2-5079H |
Product Overview : | Human HSD3B2 full-length ORF ( NP_000189.1, 1 a.a. - 372 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 68.5 kDa |
AA Sequence : | MGWSCLVTGAGGLLGQRIVRLLVEE KELKEIRALDKAFRPELREEFSKLQ NRTKLTVLEGDILDEPFLKRACQDV SVVIHTACIIDVFGVTHRESIMNVN VKGTQLLLEACVQASVPVFIYTSSI EVAGPNSYKEIIQNGHEEEPLENTW PTPYPYSKKLAEKAVLAANGWNLKN GDTLYTCALRPTYIYGEGGPFLSAS INEALNNNGILSSVGKFSTVNPVYV GNVAWAHILALRALRDPKKAPSVRG QFYYISDDTPHQSYDNLNYILSKEF GLRLDSRWSLPLTLMYWIGFLLEVV SFLLSPIYSYQPPFNRHTVTLSNSV FTFSYKKAQRDLAYKPLYSWEEAKQ KTVEWVGSLVDRHKETLKSKTQ |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 [ Homo sapiens ] |
Official Symbol : | HSD3B2 |
Synonyms : | HSD3B2; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2; SDR11E2; short chain dehydrogenase/reductase family 11E; member 2; 3 beta-hydroxysteroid dehydrogenase/Delta 5--> 4-isomerase type 2; 3-beta-HSD II; 3 beta-HSD type II; progesterone reductase; delta 5-delta 4-isomerase type II; 3-beta-HSD adrenal and gonadal type; 3-beta-hydroxy-5-ene steroid dehydrogenase; 3-beta-hydroxy-Delta(5)-steroid dehydrogenase; short chain dehydrogenase/reductase family 11E, member 2; 4-isomerase type II; 3 beta-hydroxysteroid dehydrogenase type II, delta 5-delta 4-isomerase type II, 3 beta-HSD type II; HSDB; HSD3B; |
Gene ID : | 3284 |
mRNA Refseq : | NM_000198 |
Protein Refseq : | NP_000189 |
MIM : | 613890 |
UniProt ID : | P26439 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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