Recombinant Human ICAM1 Protein, MYC/DDK-tagged
Cat.No. : | ICAM1-799H |
Product Overview : | Recombinant human ICAM1 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008]. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol. |
Molecular Mass : | 55.2 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | intercellular adhesion molecule 1[ Homo sapiens ] |
Official Symbol : | ICAM1 |
Synonyms : | BB2; CD54; P3.58 |
Gene ID : | 3383 |
mRNA Refseq : | NM_000201 |
Protein Refseq : | NP_000192 |
MIM : | 147840 |
UniProt ID : | P05362 |
Products Types
◆ Recombinant Protein | ||
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ICAM1-4320B | Recombinant Bovine ICAM1 Protein | +Inquiry |
ICAM1-2266R | Recombinant Rabbit ICAM1 Protein, His&SUMO-tagged | +Inquiry |
Icam1-1204M | Recombinant Mouse Icam1 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
ICAM1-1970RCL | Recombinant Rat ICAM1 cell lysate | +Inquiry |
ICAM1-2655HCL | Recombinant Human ICAM1 cell lysate | +Inquiry |
ICAM1-2487MCL | Recombinant Mouse ICAM1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, targeting ICAM1 is being explored as a potential therapeutic strategy for inflammatory diseases, with research focusing on developing ICAM1 inhibitors.
ICAM1 is upregulated during inflammation, promoting the adhesion of immune cells to the endothelium and facilitating their migration into inflamed tissues.
ICAM1 expression can be altered in cancer cells and is implicated in promoting cancer progression by facilitating tumor cell adhesion, invasion, and metastasis.
ICAM1 levels can be measured in blood or tissue samples, and elevated levels may serve as diagnostic markers for certain inflammatory diseases.
Elevated levels of ICAM1 in some diseases may serve as prognostic markers, indicating disease severity and potential outcomes.
Customer Reviews (3)
Write a reviewManufacturers may provide documentation of the protein's validation, which includes information about its purity, concentration, stability, and potential contaminants.
This can be particularly important in clinical trials to ensure accurate and reliable results.
If the need arises for larger quantities of ICAM1 protein during the later stages of clinical trials, the manufacturer can facilitate scale-up production processes to meet those requirements.
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