Recombinant Human IGF1 Protein
Cat.No. : | IGF1-140H |
Product Overview : | Recombinant Human Insulin-like Growth Factor I is produced by our E.coli expression system and the target gene encoding Gly49-Ala118 is expressed. |
- Specification
- Gene Information
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Description : | Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contains the N- and C-terminal propeptide regions. Mature human IGF-I consisting of 70 amino acids has 94% identity with mouse IGF-I and exhibits cross-species activity. IGF-1 binds IGF-IR, IGF-IIR, and the insulin receptor and plays a key role in cell cycle progression, cell proliferation and tumor progression. IGF-1 expression is regulated by growth hormone. R3 IGF-1 is an 83 amino acid analog of IGF-1 comprising the complete human IGF-1 sequence with the substitution of an Arg (R) for the Glu(E) at position three, hence R3, and a 13 amino acid extension peptide at the N terminus. R3 IGF-1 has been produced with the purpose of increasing biological activity. R3 IGF-1 is significantly more potent than human IGF-I in vitro. |
Source : | E. coli |
Species : | Human |
Form : | Lyophilized from a 0.2 um filtered solution of 300mM NaAc, pH 6.5. |
AA Sequence : | Gly49-Ala118 |
Endotoxin : | Less than 0.1 ng/ug (1 EU/ug). |
Shipping : | Ambient |
Gene Name : | IGF1 insulin like growth factor 1 [ Homo sapiens (human) ] |
Official Symbol : | IGF1 |
Synonyms : | Insulin-Like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IBP1; IGF; MGF; IGFI |
Gene ID : | 3479 |
mRNA Refseq : | NM_000618.5 |
Protein Refseq : | NP_000609.1 |
MIM : | 147440 |
UniProt ID : | P05019 |
Products Types
◆ Lysates | ||
IGF1-5268HCL | Recombinant Human IGF1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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