Recombinant Human IGF2BP3 Protein, GST-tagged

• Cat.No.: IGF2BP3-5147H
• Product Overview: Human IMP-3 full-length ORF ( AAH65269, 1 a.a. - 579 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5 UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 89.43 kDa
• AA Sequence: MNKLYIGNLSENAAPSDLESIFKDA KIPVSGPFLVKTGHAFVDCPDESWA LKAIEALSGKIELHGKPIEVEHSVP KRQRIRKLQIRNIPPHLQWEVLDSL LVQYGVVESCEQVNTDSETAVVNVT YSSKDQARQALDKLNGFQLENFTLK VAYIPDEMAAQQNPLQQPRGRRGLG QRGSSRQGSPGSVSKQKPCDLPLRL LVPTQFVGAIIGKEGATIRNITKQT QSKIDVHRKENAGAAEKSITILSTP EGTSAACKSILEIMHKEAQDIKFTE EIPLKILAHNNFVGRLIGKEGRNLK KIEQDTDTKITISPLQELTLYNPER TITVKGNVETCAKAEEEIMKKIRES YENDIASMNLQAHLIPGLNLNALGL FPPTSGMPPPTSGPPSAMTPPYPQF EQSETETVHLFIPALSVGAIIGKQG QHIKQLSRFAGASIKIAPAEAPDAK VRMVIITGPPEAQFKAQGRIYGKIK EENFVSPKEEVKLEAHIRVPSFAAG RVIGKGGKTVNELQNLSSAEVVVPR DQTPDENDQVVVKITGHFYACQVAQ RKIQEILTQVKQHQQQKALQSGPPQ SRRK
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 [ Homo sapiens ]
• Official Symbol: IGF2BP3
• Synonyms: IGF2BP3; insulin-like growth factor 2 mRNA binding protein 3; insulin-like growth factor 2 mRNA-binding protein 3; cancer/testis antigen 98; CT98; IGF II mRNA binding protein 3; IMP 3; hKOC; VICKZ family member 3; IGF2 mRNA-binding protein 3; IGF-II mRNA-binding protein 3; KH domain containing protein overexpressed in cancer; KH domain-containing protein overexpressed in cancer; IMP3; KOC1; IMP-3; VICKZ3; DKFZp686F1078
• Gene ID: 10643
• mRNA Refseq: NM_006547
• Protein Refseq: NP_006538
• MIM: 608259
• UniProt ID: O00425