Active Recombinant Human IL15 Protein
Cat.No. : | IL15-063H |
Product Overview : | Recombinant human IL-15 protein consisting of 115 amino acid residues (Asn49-Ser162) without tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported. |
Source : | E. coli |
Species : | Human |
Bio-activity : | Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. The ED50 for this effect is 0.3-2.6 ng/mL. |
Molecular Mass : | 12.9 kDa |
Product-Related Proteins : | 49-162 |
Endotoxin : | < 0.1 EU/μg of the protein as determined by the LAL method |
Purity : | > 95 % as determined by SDS-PAGE |
Storage : | At -80 centigrade. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | PBS |
Gene Name : | IL15 interleukin 15 [ Homo sapiens (human) ] |
Official Symbol : | IL15 |
Synonyms : | IL15; interleukin 15; IL-15; interleukin-15 |
Gene ID : | 3600 |
mRNA Refseq : | NM_000585 |
Protein Refseq : | NP_000576 |
MIM : | 600554 |
UniProt ID : | P40933 |
Products Types
◆ Recombinant Protein | ||
IL15-370I | Active Recombinant Human IL15 Protein (121 aa), His-tagged | +Inquiry |
IL15-369I | Active Recombinant Human IL15 Protein (114 aa) | +Inquiry |
IL15-1004P | Recombinant Pig IL15 Protein, His-tagged | +Inquiry |
IL15-382H | Active Recombinant Human IL15 protein(Asn49-Ser162) | +Inquiry |
Il15-146M | Recombinant Active Mouse IL15 Protein, His-tagged(N-ter) | +Inquiry |
◆ Lysates | ||
IL15-5248HCL | Recombinant Human IL15 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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