Recombinant Human IL1B, His-tagged
Cat.No. : | IL1B-321H |
Product Overview : | IL1B Human Recombinant produced in E.Coli is a single, non-glycosylated, His-Tag Polypeptide chain containing 153 amino acids fragment (117-269) and having a total molecular mass of 21.88 kDa with an amino-terminal hexahistidine tag. The IL-1B His is purified by proprietary chromatographic techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | IL1B-321H |
Description : | IL1B is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1 alpha and IL1B binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL1B is a secreted cytokine, IL-1 alpha is predominantly a cell-associated cytokine. |
Source : | E. coli |
Species : | Human |
Form : | IL1B His is supplied in 1μ PBS and 50% glycerol. |
Research topic : | Energy metabolism and body weight regulation |
Purity : | >95% |
Reconstitution : | Add deionized water to prepare a working stock solution of approximately 0.5 mg/mL and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture. |
Storage : | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles. |
Gene Name : | IL1B interleukin 1, beta [ Homo sapiens ] |
Official Symbol : | IL1B |
Synonyms : | IL1B; interleukin 1, beta; IL-1; IL1F2; IL1-BETA; interleukin-1 beta; IL-1 beta; catabolin; OTTHUMP00000162031; preinterleukin 1 beta; pro-interleukin-1-beta |
Gene ID : | 3553 |
mRNA Refseq : | NM_000576 |
Protein Refseq : | NP_000567 |
MIM : | 147720 |
UniProt ID : | P01584 |
Chromosome Location : | 2q14 |
Pathway : | African trypanosomiasis; Alzheimer"s disease; Amoebiasis; Apoptosis; Cellular roles of Anthrax toxin; Cytokine-cytokine receptor interaction; Cytosolic DNA-sensing pathway; Graft-versus-host disease; Hematopoietic cell lineage; IFN-gamma pathway; IL-1 Signaling Pathway; IL12-mediated signaling events; IL27-mediated signaling events; IL23-mediated signaling events; Influenza A |
Function : | cytokine activity; growth factor activity; interleukin-1 receptor binding; protein binding; protein domain specific binding |
Products Types
◆ Recombinant Protein | ||
IL1B-2060R | Recombinant Rhesus Macaque IL1B Protein, His (Fc)-Avi-tagged | +Inquiry |
IL1B-151M | Active Recombinant Mouse IL1B Protein | +Inquiry |
Il1B-466H | Recombinant Human Il1B, HIgG1 Fc-tagged | +Inquiry |
IL1B-920C | Active Recombinant Canine IL1B Protein (Ala115-Ser266) | +Inquiry |
Il1b-365I | Active Recombinant Mouse Il1b Protein (153 aa) | +Inquiry |
◆ Lysates | ||
IL1B-853HCL | Recombinant Human IL1B cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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