Active Recombinant Human IL21 Protein (aa 32-162), N-Fc-tagged
Cat.No. : | IL21-01H |
Product Overview : | The extracellular domain of human IL-21 (aa 32-162) is fused to the N-terminus of the Fc region of a mutant human IgG4 was expressed in CHO. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Source : | CHO |
Species : | Human |
Tag : | N-hFc |
Bio-activity : | Measured in a cell proliferation assay using N1186 human T cells. |
Molecular Mass : | ~42 kDa (SDS-PAGE) |
Protein Length : | 32-162 |
Endotoxin : | <5 EU/mg protein (LAL test; Lonza). |
Purity : | ≥95% (SDS-PAGE) |
Stability : | Stable for at least 1 year after receipt when stored at -20 centigrade. Working aliquots are stable for up to 3 months when stored at -20 centigrade. |
Storage : | Short Term Storage: +4 centigrade Long Term Storage: -20 centigrade |
Storage Buffer : | Lyophilized from 0.2 μm-filtered solution in PBS. |
Reconstitution : | Reconstitute 50 μg vial in 50 μL sterile water. Add 1 × PBS to the desired protein concentration. |
Handling : | Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. |
Shipping : | BLUE ICE |
Gene Name : | IL21 interleukin 21 [ Homo sapiens (human) ] |
Official Symbol : | IL21 |
Synonyms : | IL21; interleukin 21; Za11; IL-21; CVID11; interleukin-21 |
Gene ID : | 59067 |
mRNA Refseq : | NM_021803 |
Protein Refseq : | NP_068575 |
MIM : | 605384 |
UniProt ID : | Q9HBE4 |
Products Types
◆ Recombinant Protein | ||
IL21-2300H | Recombinant Human IL21 Protein, His-tagged | +Inquiry |
IL21-4336R | Recombinant Rabbit IL21 Protein | +Inquiry |
Il21-3511M | Active Recombinant Mouse Il21 Protein | +Inquiry |
IL21-735H | Active Recombinant Human IL21 Protein | +Inquiry |
Il21-265M | Active Recombinant Mouse Il21 Protein (His18-Ser146), C-His tagged, Animal-free, Carrier-free | +Inquiry |
◆ Lysates | ||
IL21-001RCL | Recombinant Rat IL21 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket