Recombinant Human IL22 Protein, His-tagged
Cat.No. : | IL22-91H |
Product Overview : | Recombinant Human Interleukin-22 is produced by our Mammalian expression system and the target gene encoding Ala34-Ile179 is expressed with a 6His tag at the C-terminus. |
- Specification
- Gene Information
- Related Products
Description : | Interleukin-22(IL-22) is a member of a group of the IL-10 family, a class of potent mediators of cellular inflammatory responses. IL-22 is produced by activated DC and T cells. IL-22 and IL-10 receptor chains play a role in cellular targeting and signal transduction. It can initiate and regulate innate immune responses against bacterial pathogens especially in epithelial cells such as respiratory and gut epithelial cells. IL-22 along with IL-17 likely plays a role in the coordinated response of both adaptive and innate immune systems. IL-22 also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10. Biological activity of IL-22 is initiated by binding to a cell-surface complex consisting of IL-22R1 and IL-10R2 receptor chains. IL-22 biological activity is further regulated by interactions with a soluble binding protein, IL-22BP. IL-22BP and an extracellular region of IL-22R1 share sequence similarity. In some cases, the pro-inflammatory versus tissue-protective functions of IL-22 are regulated by cytokine IL-17A. |
Source : | Human Cells |
Species : | Human |
Tag : | His |
Form : | Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. |
AA Sequence : | Ala34-Ile179 |
Endotoxin : | Less than 0.1 ng/ug (1 EU/ug). |
Shipping : | Ambient |
Gene Name : | IL22 interleukin 22 [ Homo sapiens (human) ] |
Official Symbol : | IL22 |
Synonyms : | Interleukin-22; IL-22; Cytokine Zcyto18; IL-10-related T-cell-derived-inducible factor; IL22; ZCYTO18; TIFa; IL-21; IL-22; ILTIF; IL-TIF; IL-D110; zcyto18; TIFIL-23 |
Gene ID : | 50616 |
mRNA Refseq : | NM_020525.5 |
Protein Refseq : | NP_065386.1 |
MIM : | 605330 |
UniProt ID : | Q9GZX6 |
Products Types
◆ Recombinant Protein | ||
IL22-2066R | Recombinant Rhesus Macaque IL22 Protein, His (Fc)-Avi-tagged | +Inquiry |
IL22-44H | Recombinant Human IL22 Protein, C-6His tagged, Biotinylated | +Inquiry |
IL22-098I | Active Recombinant Human IL22 Protein (146 aa) | +Inquiry |
IL22-4348S | Recombinant Sheep IL22 Protein | +Inquiry |
IL22-178I | Active Recombinant Human IL22 Protein | +Inquiry |
◆ Lysates | ||
IL22-5232HCL | Recombinant Human IL22 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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