Recombinant Human IL6R Protein, GST-tagged
|Product Overview :
|Human IL6R full-length ORF ( NP_000556.1, 1 a.a. - 468 a.a.) recombinant protein with GST-tag at N-terminal.
- Gene Information
- Related Products
|Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. The protein encoded by this gene is a subunit of the receptor complex for IL6. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
|Molecular Mass :
|AA Sequence :
|MLAVGCALLAALLAAPGAALAPRRC PAQEVARGVLTSLPGDSVTLTCPGV EPEDNATVHWVLRKPAAGSHPSRWA GMGRRLLLRSVQLHDSGNYSCYRAG RPAGTVHLLVDVPPEEPQLSCFRKS PLSNVVCEWGPRSTPSLTTKAVLLV RKFQNSPAEDFQEPCQYSQESQKFS CQLAVPEGDSSFYIVSMCVASSVGS KFSKTQTFQGCGILQPDPPANITVT AVARNPRWLSVTWQDPHSWNSSFYR LRFELRYRAERSKTFTTWMVKDLQH HCVIHDAWSGLRHVVQLRAQEEFGQ GEWSEWSPEAMGTPWTESRSPPAEN EVSTPMQALTTNKDDDNILFRDSAN ATSLPVQDSSSVPLPTFLVAGGSLA FGTLLCIAIVLRFKKTWKLRALKEG KTSMHPPYSLGQLVPERPRPTPVLV PLISPPVSPSSLGSDNTSSHNRPDA RDPRSPYDISNTDYFFPR
|Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
|Best use within three months from the date of receipt of this protein.
|Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
|Storage Buffer :
|50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
|Gene Name :
|IL6R interleukin 6 receptor [ Homo sapiens ]
|Official Symbol :
|IL6R; interleukin 6 receptor; interleukin-6 receptor subunit alpha; CD126; IL-6R 1; CD126 antigen; membrane glycoprotein 80; IL-6 receptor subunit alpha; gp80; IL6RA; IL-6RA; IL-6R-1; MGC104991;
|Gene ID :
|mRNA Refseq :
|Protein Refseq :
|UniProt ID :
|◆ Recombinant Protein
|Recombinant Human IL-6 Protein
|Recombinant Human IL6R Protein, C13 and N15 Labeled
|Recombinant Human IL6R Protein, His-tagged
|Active Recombinant Human IL6R Protein (350 aa), N-His-tagged
|Active Recombinant Human IL6R Protein
|Recombinant Human IL6R cell lysate
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (6)Ask a question
The dose and route of administration need to be determined according to the specific treatment situation. Common routes of administration include subcutaneous injection and intravenous injection.
It can be used to treat certain autoimmune diseases, such as rheumatoid arthritis and psoriasis.
The IL6R is primarily used to treat inflammatory diseases that have already occurred, rather than prevent them.
IL6R reduces inflammation by binding to interleukin-6 (IL-6), blocking the IL-6 signaling pathway.
Although IL6R can regulate the immune system, it is not a direct anti-tumor drug.
The efficacy of IL6R is usually evaluated based on improvement of clinical symptoms, changes in disease activity, and changes in biochemical markers.
Customer Reviews (3)Write a review
Good compatibility and stability with the surfactant.
Expression level and stability of clones were good.
Remarkable antibacterial activity and bactericidal effect on bacteria.
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