Active Recombinant Human IL6ST protein, His-tagged
Cat.No. : | IL6ST-1300H |
Product Overview : | Recombinant Human IL6ST protein(Glu 23 - Glu 619), fused with His tag, was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant. |
Bio-activity : | Immobilized Biotinylated Human IL-6 R alpha, Fc,Avitag can bind Human gp130, His Tag with a linear range of 0.005-0.313 μg/mL.Immobilized Human gp130, His Tag can bind Biotinylated Human IL-6 R alpha, Fc,Avitag with a linear range of 0.6-20 ng/mL. |
Molecular Mass : | This protein carries a polyhistidine tag at the C-terminusThe protein has a calculated MW of 69.6 kDa. The protein migrates as 80-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein Length : | Glu23-Glu619 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. >90% as determined by SEC-MALS. |
Storage : | For long term, the product should be stored at lyophilized state at -20°C or lower.Please protect from light and avoid repeated freeze-thaw cycles.This product is stable after at: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | IL6ST interleukin 6 signal transducer (gp130, oncostatin M receptor) [ Homo sapiens ] |
Official Symbol : | IL6ST |
Synonyms : | IL6ST; interleukin 6 signal transducer (gp130, oncostatin M receptor); interleukin-6 receptor subunit beta; CD130; GP130; CD130 antigen; IL-6R subunit beta; membrane glycoprotein 130; IL-6 receptor subunit beta; membrane glycoprotein gp130; interleukin receptor beta chain; oncostatin-M receptor subunit alpha; gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form; CDW130; IL-6RB; DKFZp564F053; |
Gene ID : | 3572 |
mRNA Refseq : | NM_001190981 |
Protein Refseq : | NP_001177910 |
MIM : | 600694 |
UniProt ID : | P40189 |
Products Types
◆ Recombinant Protein | ||
IL6ST-2076R | Recombinant Rhesus Macaque IL6ST Protein, His (Fc)-Avi-tagged | +Inquiry |
Il6st-275M | Recombinant Mouse Il6st Protein, Fc-tagged | +Inquiry |
Il6st-26R | Recombinant Rat Il6st Protein, His (Fc)-Avi-tagged | +Inquiry |
IL6ST-1380H | Acitve Recombinant Human IL6ST protein(Met1-Ile618), His&hFc-tagged | +Inquiry |
IL6ST-2749H | Recombinant Human IL6ST protein(771-910 aa), C-His-tagged | +Inquiry |
◆ Lysates | ||
IL6ST-1882RCL | Recombinant Rat IL6ST cell lysate | +Inquiry |
IL6ST-001MCL | Recombinant Mouse IL6ST cell lysate | +Inquiry |
IL6ST-946CCL | Recombinant Cynomolgus IL6ST cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
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Q&As (6)
Ask a questionThe activity of IL6ST is usually detected by cell differentiation and proliferation assay.
IL6ST may be used in the future to treat pulmonary fibrosis, chronic pulmonary obstruction, rheumatoid arthritis, and other chronic kidney diseases.
IL6ST is involved in various inflammatory responses and cell differentiation processes.
The physical and chemical properties of IL6ST include molecular weight, voltammetry potential, structure and stability.
The study of IL6ST helps us to better understand the disease mechanism involved in IL6ST, and provides new ideas and means for disease treatment.
The IL6ST is usually prepared by transforming E. coli into an expression vector and making it express the IL6ST protein.
Customer Reviews (3)
Write a reviewIL6ST proteins can be functionally enhanced or altered by protein modification techniques.
As an immunotherapy drug, it has good effect and high safety.
Has a good inhibitory effect on cell proliferation and survival.
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