Recombinant Human IL6ST Protein, Fc-tagged

• Cat.No.: IL6ST-265H
• Product Overview: Recombinant human IL6ST (AAA59155.1) (Met1-Ile618) was expressed with the Fc region of human IgG1 at the C-terminus.

Specification

• Species: Human
• Source: HEK293
• Tag: Fc
• Protein Length: 1-618 a.a.
• Predicted N Terminal: Glu 23
• Form: Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol.
• Molecular Mass: The recombinant human IL6ST consists 834 amino acids and predicts a molecular mass of 94.4 kDa.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >90 % as determined by SDS-PAGE.
• Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
• Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: IL6ST interleukin 6 signal transducer (gp130, oncostatin M receptor) [ Homo sapiens ]
• Official Symbol: IL6ST
• Synonyms: IL6ST; interleukin 6 signal transducer (gp130, oncostatin M receptor); interleukin-6 receptor subunit beta; CD130; GP130; CD130 antigen; IL-6R subunit beta; membrane glycoprotein 130; IL-6 receptor subunit beta; membrane glycoprotein gp130; interleukin receptor beta chain; oncostatin-M receptor subunit alpha; gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form; CDW130; IL-6RB; DKFZp564F053
• Gene ID: 3572
• mRNA Refseq: NM_001190981
• Protein Refseq: NP_001177910
• MIM: 600694
• UniProt ID: P40189
• Chromosome Location: 5q11.2
• Pathway: Adipogenesis, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; IL-6 Signaling Pathway, organism-specific biosystem; IL27-mediated signaling events, organism-specific biosystem