Recombinant Human IMPDH2 Protein (Met1-Phe514), N-His tagged

• Cat.No.: IMPDH2-2578H
• Product Overview: Recombinant human IMPDH2 (Met1-Phe514) protein fused with the N-terminal His tag was expressed in E. coli.

Specification

• Description: This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy-and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
• Source: E. coli
• Species: Human
• Tag: N-His
• Molecular Mass: 56.54 kDa
• Protein Length: Met1-Phe514
• Purity: >90 % as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS or lyophilized from PBS.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: IMPDH2 IMP (inosine 5-monophosphate) dehydrogenase 2 [ Homo sapiens (human) ]
• Official Symbol: IMPDH2
• Synonyms: IMPDH2; IMP (inosine 5-monophosphate) dehydrogenase 2; inosine-5-monophosphate dehydrogenase 2; IMPD 2; IMPDH 2; IMP oxireductase 2; inosine 5 phosphate dehydrogenase 2; IMP (inosine monophosphate) dehydrogenase 2; inosine monophosphate dehydrogenase type II; IMPD2; IMPDH-II
• Gene ID: 3615
• mRNA Refseq: NM_000884
• Protein Refseq: NP_000875
• MIM: 146691
• UniProt ID: P12268