Recombinant Mouse IMPDH2 Protein, His-tagged

• Cat.No.: IMPDH2-62M
• Product Overview: Recombinant Mouse IMPDH2 Protein, fused to His-tag, was expressed in E. coli.

Specification

• Description: Enables IMP dehydrogenase activity. Involved in 'de novo' XMP biosynthetic process and GMP biosynthetic process. Acts upstream of or within cellular response to interleukin-4; lymphocyte proliferation; and purine nucleotide biosynthetic process. Predicted to be located in cytosol and nucleus. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; brain; heart; respiratory system; and sensory organ. Orthologous to human IMPDH2 (inosine monophosphate dehydrogenase 2).
• Source: E. coli
• Species: Mouse
• Tag: His
• Form: 50mM Tris, 0.3 M NaCl, pH 8.0.
• Molecular Mass: 56.7kDa
• AA Sequence: MHHHHHHMADYLISGGTSYVPDDGL TAQQLFNCGDGLTYNDFLILPGYID FTADQVDLTSALTKKITLKTPLVSS PMDTVTEAGMAIAMALTGGIGFIHH NCTPEFQANEVRKVKKYEQGFITDP VVLSPKDRVRDVFEAKARHGFCGIP ITDTGRMGSRLVGIISSRDIDFLKE EEHDRFLEEIMTKREDLVVAPAGVT LKEANEILQRSKKGKLPIVNENDEL VAIIARTDLKKNRDYPLASKDAKKQ LLCGAAIGTHEDDKYRLDLLALAGV DVVVLDSSQGNSIFQINMIKYIKEK YPSLQVIGGNVVTAAQAKNLIDAGV DALRVGMGSGSICITQEVLACGRPQ ATAVYKVSEYARRFGVPVIADGGIQ NVGHIAKALALGASTVMMGSLLAAT TEAPGEYFFSDGIRLKKYRGMGSLD AMDKHLSSQNRYFSEADKIKVAQGV SGAVQDKGSIHKFVPYLIAGIQHSC QDIGAKSLTQVRAMMYSGELKFEKR TSSAQVEGGVHSLHSYEKRLF
• Purity: >90%
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 2.1 mg/mL

Gene Information

• Gene Name: Impdh2 inosine monophosphate dehydrogenase 2 [ Mus musculus (house mouse) ]
• Official Symbol: IMPDH2
• Synonyms: IMPD; IMPD 2; IMPDH-II
• Gene ID: 23918
• mRNA Refseq: NM_011830
• Protein Refseq: NP_035960
• UniProt ID: P24547