Recombinant Human IRAK2 IRAK2-27503TH

Recombinant Human IRAK2

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Cat.No. : IRAK2-27503TH Optional Service: Optional requirements on this protein
Product Overview : Recombinant full length Human IRAK2 with N-terminal proprietary tag; MWt 103kDa.
Description : IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB.
Protein length : 625 amino acids
Molecular Weight : 103.000kDa inclusive of tags
Source : Baculovirus
Biological activity : The specific activity of IRAK2-27503TH was determined to be 6 nmol/min/mg.
Form : Liquid
Storage buffer : Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Gene Name : IRAK2 interleukin-1 receptor-associated kinase 2 [ Homo sapiens ]
Official Symbol : IRAK2
Synonyms : IRAK2; interleukin-1 receptor-associated kinase 2; interleukin-1 receptor-associated kinase-like 2;
Gene ID : 3656
mRNA Refseq : NM_001570
Protein Refseq : NP_001561
MIM : 603304
Uniprot ID : O43187
Chromosome Location : 3p25.2
Pathway : Activated TLR4 signalling, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; IL-1 Signaling Pathway, organism-specific biosystem;
Function : ATP binding; NF-kappaB-inducing kinase activity; nucleotide binding; protein binding; protein heterodimerization activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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