Recombinant Human IRF4 Protein, GST-tagged

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Recombinant Human IRF4 Protein, GST-tagged

IRF4 Related Products

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Cat.No. : IRF4-5039H
Product Overview : Human IRF4 full-length ORF ( AAH15752.1, 1 a.a. - 451 a.a.) recombinant protein with GST-tag at N-terminal.
Description : The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 75.35 kDa
AA Sequence : MNLEGGGRGGEFGMS AVSCGNGKLRQWLID QIDSGKYPGLVWENE EKSIFRIPWKHAGKQ DYNREEDAALFKAWA LFKGKFREGIDKPDP PTWKTRLRCALNKSN DFEELVERSQLDISD PYKVYRIVPEGAKKG AKQLTLEDPQMSMSH PYTMTTPYPSLPAQQ VHNYMMPPLDRSWRD YVPDQPHPEIPYQCP MTFGPRGHHWQGPAC ENGCQVTGTFYACAP PESQAPGVPTEPSIR SAEALAFSDCRLHIC LYYREILVKELTTSS PEGCRISHGHTYDAS NLDQVLLPYPEDNGQ RKNIEKLLSHLERGV VPWMAPDGLYAKRLC QSRIYWDGPLALCND RPNKLERDQTCKLFD TQQFLSELQAFAHHG RSLPRFQVTLCFGEE FPDPQRQRKLITAHV EPLLARQLYYFAQQN SGHFLRGYDLPEHIS NPEDYHRSIRHSSIQ E
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue

Gene Name : IRF4 interferon regulatory factor 4 [ Homo sapiens ]
Official Symbol : IRF4
Synonyms : IRF4; interferon regulatory factor 4; MUM1; LSIRF; multiple myeloma oncogene 1; lymphocyte-specific interferon regulatory factor; NF-EM5;
Gene ID : 3662
mRNA Refseq : NM_001195286
Protein Refseq : NP_001182215
MIM : 601900
UniProt ID : Q15306

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