Recombinant Human LAIR1 Protein, His-tagged
Cat.No. : | LAIR1-091H |
Product Overview : | Recombinant Human LAIR1 Protein with His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | LAIR-1 is an inhibitory receptor that belongs to the Immunoglobulin superfamily. It has one extracellular Ig-like domain and an intracellular C-terminus with two ITIM (immunoreceptor tyrosine-based inhibitory motif) domains. It is found on peripheral mononuclear cells, including NK, T, and B cells, and is thought to play a negative regulatory role on the cytolytic function of these cells through signaling through collagen ligation. LAIR1 has been noted to be upregulated in renal cell carcinoma, and may play a role in expansion of Th17 cell populations in collagen-rich environments, such as in graft rejection tissue. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Molecular Mass : | ~20 kDa |
AA Sequence : | QEEDLPRPSISAEPGTVIPLGSHVT FVCRGPVGVQTFRLERESRSTYNDT EDVSQASPSESEARFRIDSVSEGNA GPYRCIYYKPPKWSEQSDYLELLVK ETSGGPDSPDTEPGSSAGPTQRPSD NSHNEHAPASQGLKAEHLY |
Purity : | Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE). |
Notes : | For research use only, not for use in diagnostic procedure. |
Storage : | Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles. |
Concentration : | ≥0.5 mg/mL |
Storage Buffer : | PBS, 4M Urea, pH7.4 |
Gene Name : | LAIR1 leukocyte-associated immunoglobulin-like receptor 1 [ Homo sapiens (human) ] |
Official Symbol : | LAIR1 |
Synonyms : | LAIR1; leukocyte-associated immunoglobulin-like receptor 1; leukocyte associated Ig like receptor 1; CD305; hLAIR1; leukocyte-associated Ig-like receptor 1; LAIR-1; |
Gene ID : | 3903 |
mRNA Refseq : | NM_002287 |
Protein Refseq : | NP_002278 |
MIM : | 602992 |
UniProt ID : | Q6GTX8 |
Products Types
◆ Recombinant Protein | ||
Lair1-1728M | Recombinant Mouse Lair1 Protein, His-tagged | +Inquiry |
LAIR1-3001R | Recombinant Rat LAIR1 Protein, His (Fc)-Avi-tagged | +Inquiry |
LAIR1-3325H | Recombinant Human LAIR1 Protein, His (Fc)-Avi-tagged | +Inquiry |
LAIR1-092H | Recombinant Human LAIR1 Protein, C-His-tagged | +Inquiry |
LAIR1-166H | Recombinant Human LAIR1 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
LAIR1-1331MCL | Recombinant Mouse LAIR1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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