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Recombinant Human LCK protein, Flag-tagged, Biotinylated

Cat.No.: LCK-60H
Product Overview: Recombinant Human LCK [1-509(end) amino acids of accession number NP_005347.2] fused with DYKDDDDK tag at N-terminal was expressed in insect cell and biotinylated.
Source: Insect cell
Species: Human
Tag: Flag
Form: 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5
Molecular Mass: 62 kDa
Purity: >90% as determined by SDS-PAGE and CBB staining
Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Gene Name: LCK lymphocyte-specific protein tyrosine kinase [ Homo sapiens ]
Official Symbol: LCK
Synonyms: LCK; lymphocyte-specific protein tyrosine kinase; LSK; YT16; p56lck; pp58lck;
Gene ID: 3932
mRNA Refseq: NM_001042771
Protein Refseq: NP_001036236
MIM: 153390
UniProt ID: P06239
Chromosome Location: 1p34.3
Pathway: Adaptive Immune System, organism-specific biosystem; Alpha-synuclein signaling, organism-specific biosystem; Atypical NF-kappaB pathway, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; CD28 co-stimulation, organism-specific biosystem; CD28 dependent PI3K/Akt signaling, organism-specific biosystem; CD28 dependent Vav1 pathway, organism-specific biosystem;
Function: ATP binding; ATPase binding; CD4 receptor binding; CD8 receptor binding; SH2 domain binding; SH2 domain binding; antigen binding; glycoprotein binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; phosphatidylinositol 3-kinase binding; protein C-terminus binding; protein binding; protein complex binding; protein kinase binding; protein serine/threonine phosphatase activity; protein serine/threonine phosphatase activity; protein tyrosine kinase activity; protein tyrosine kinase activity; protein tyrosine kinase activity; protein tyrosine kinase activity; protein tyrosine phosphatase activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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