Cat.No. : | LCK-60H |
Product Overview : | Recombinant Human LCK [1-509(end) amino acids of accession number NP_005347.2] fused with DYKDDDDK tag at N-terminal was expressed in insect cell and biotinylated. |
Source : | Insect cell |
Species : | Human |
Tag : | Flag |
Form : | 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5 |
Molecular Mass : | 62 kDa |
Purity : | >90% as determined by SDS-PAGE and CBB staining |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Gene Name : | LCK lymphocyte-specific protein tyrosine kinase [ Homo sapiens ] |
Official Symbol : | LCK |
Synonyms : | LCK; lymphocyte-specific protein tyrosine kinase; LSK; YT16; p56lck; pp58lck; |
Gene ID : | 3932 |
mRNA Refseq : | NM_001042771 |
Protein Refseq : | NP_001036236 |
MIM : | 153390 |
UniProt ID : | P06239 |
Chromosome Location : | 1p34.3 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Alpha-synuclein signaling, organism-specific biosystem; Atypical NF-kappaB pathway, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; CD28 co-stimulation, organism-specific biosystem; CD28 dependent PI3K/Akt signaling, organism-specific biosystem; CD28 dependent Vav1 pathway, organism-specific biosystem; |
Function : | ATP binding; ATPase binding; CD4 receptor binding; CD8 receptor binding; SH2 domain binding; SH2 domain binding; antigen binding; glycoprotein binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; phosphatidylinositol 3-kinase binding; protein C-terminus binding; protein binding; protein complex binding; protein kinase binding; protein serine/threonine phosphatase activity; protein serine/threonine phosphatase activity; protein tyrosine kinase activity; protein tyrosine kinase activity; protein tyrosine kinase activity; protein tyrosine kinase activity; protein tyrosine phosphatase activity; |
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