Recombinant Human LIN28A Protein

• Cat.No.: LIN28A-643H
• Product Overview: Recombinant human LIN28A protein, fused to 13-TAT tag at C-terminus, was expressed in E. coli.

Specification

• Description: This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues. [provided by RefSeq, Sep 2015].
• Source: E. coli
• Species: Human
• Form: Lyophilized from a 0.2 µM filtered solution of 20 mM phosphate buffer, 100 mM NaCl, pH 7.2
• Molecular Mass: 24.4 kDa
• Purity: >90% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: Resuspend the protein in the desired concentration in proper buffer

Gene Information

• Gene Name: lin-28 homolog A[ Homo sapiens ]
• Official Symbol: LIN28A
• Synonyms: CSDD1; LIN-28; lin-28A; LIN28; ZCCHC1
• Gene ID: 79727
• mRNA Refseq: NM_024674.4
• Protein Refseq: NP_078950.1
• MIM: 611043
• UniProt ID: Q9H9Z2