Recombinant Human MGAT1 Protein, GST-tagged

• Cat.No.: MGAT1-4371H
• Product Overview: Human MGAT1 full-length ORF ( NP_002397.1, 1 a.a. - 445 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis. Several variants encoding the same protein have been found for this gene. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 77.3 kDa
• AA Sequence: MLKKQSAGLVLWGAILFVAWNALLL LFFWTRPAPGRPPSVSALDGDPASL TREVIRLAQDAEVELERQRGLLQQI GDALSSQRGRVPTAAPPAQPRVPVT PAPAVIPILVIACDRSTVRRCLDKL LHYRPSAELFPIIVSQDCGHEETAQ AIASYGSAVTHIRQPDLSSIAVPPD HRKFQGYYKIARHYRWALGQVFRQF RFPAAVVVEDDLEVAPDFFEYFRAT YPLLKADPSLWCVSAWNDNGKEQMV DASRPELLYRTDFFPGLGWLLLAEL WAELEPKWPKAFWDDWMRRPEQRQG RACIRPEISRTMTFGRKGVSHGQFF DQHLKFIKLNQQFVHFTQLDLSYLQ REAYDRDFLARVYGAPQLQVEKVRT NDRKELGEVRVQYTGRDSFKAFAKA LGVMDDLKSGVPRAGYRGIVTFQFR GRRVHLAPPPTWEGYDPSWN
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase [ Homo sapiens ]
• Official Symbol: MGAT1
• Synonyms: MGAT1; mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase; GLYT1, MGAT; alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase; GLCNAC TI; GNT 1; glcNAc-T I; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I; MGAT; GLCT1; GLYT1; GNT-1; GNT-I; GLCNAC-TI
• Gene ID: 4245
• mRNA Refseq: NM_001114617
• Protein Refseq: NP_001108089
• MIM: 160995
• UniProt ID: P26572