Recombinant Human MLF1 protein, GST-tagged

• Cat.No.: MLF1-2390H
• Product Overview: Recombinant Human MLF1(1 a.a. - 268 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ.

Specification

• Description: This gene encodes an oncoprotein which is thought to play a role in the phenotypic determination of hemopoetic cells. Translocations between this gene and nucleophosmin have been associated with myelodysplastic syndrome and acute myeloid leukemia. Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 57 kDa
• AA Sequence: MFRMLNSSFEDDPFFSESILAHREN MRQMIRSFSEPFGRDLLSISDGRGR AHNRRGHNDGEDSLTHTDVSSFQTM DQMVSNMRNYMQKLERNFGQLSVDP NGHSFCSSSVMTYSKIGDEPPKVFQ ASTQTRRAPGGIKETRKAMRDSDSG LEKMAIGHHIHDRAHVIKKSKNKKT GDEEVNQEFINMNESDAHAFDEEWQ SEVLKYKPGRHNLGNTRMRSVGHEN PGSRELKRREKPQQSPAIEHGRRSN VLGDKLHIKGSSVKSNKK
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: MLF1 myeloid leukemia factor 1 [ Homo sapiens ]
• Official Symbol: MLF1
• Synonyms: MLF1; myeloid leukemia factor 1; myeloid leukemia factor 1 variant 1; myeloid leukemia factor 1 variant 2; myeloid leukemia factor 1 variant 3; myelodysplasia-myeloid leukemia factor 1
• Gene ID: 4291
• mRNA Refseq: NM_001130156
• Protein Refseq: NP_001123628
• MIM: 601402
• UniProt ID: P58340
• Chromosome Location: 3q25
• Pathway: Transcriptional misregulation in cancer, organism-specific biosystem; Transcriptional misregulation in cancer, conserved biosystem
• Function: DNA binding; DNA binding; protein binding; protein domain specific binding