Recombinant Human MSLN Protein, His\Avi-tagged
Cat.No. : | MSLN-181H |
Product Overview : | Biotinylated Recombinant Human Mesothelin is produced by our Mammalian expression system and thetarget gene encoding Glu296-Ser598 is expressed with a 6His, Avi tag at the C-terminus. |
- Specification
- Gene Information
- Related Products
Description : | Mesothelin is a cell surface glycoprotein whose expression is limited to mesothelial cells of the serosa (pleura, pericardium, and peritoneum) and epithelial cells of the trachea, tonsils, fallopian tube, and kidneys. Mesothelin plays an important role in cell survival, proliferation, migration, invasion, tumor progression, and resistance to chemotherapy. The overexpression of mesothelin can activate NF-κB and signal transducer and activator of transcription 3 (Stat3), inhibit apoptotic signaling and TNF-α-induced apoptosis, and accelerate the G1–S transition. Mesothelin is also found overexpressed in various cancers, including malignant mesothelioma, pancreatic or ovarian carcinoma, sarcomas and in some gastrointestinal or pulmonary carcinomas. As a result of its limited expression in normal tissues, mesothelin has been reported as an ideal tumor-associated marker for the development of targeted therapy. |
Source : | Human Cells |
Species : | Human |
Tag : | His\Avi |
Form : | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
AA Sequence : | Glu296-Ser598 |
Endotoxin : | Less than 0.1 ng/ug (1 EU/ug). |
Shipping : | Ambient |
Gene Name : | MSLN mesothelin [ Homo sapiens (human) ] |
Official Symbol : | MSLN |
Synonyms : | Megakaryocyte potentiating factor; mesothelin; Pre-pro-megakaryocyte-potentiating factor; soluble MPF mesothelin related protein; MPF; MSLN;SMR; CAK1; CAK1 antigen; SMRP |
Gene ID : | 10232 |
mRNA Refseq : | NM_001177355.3 |
Protein Refseq : | NP_001170826.1 |
MIM : | 601051 |
UniProt ID : | Q13421 |
Products Types
◆ Recombinant Protein | ||
MSLN-3449R | Recombinant Rat MSLN Protein, His (Fc)-Avi-tagged | +Inquiry |
MSLN-072H | Recombinant Human MSLN Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
MSLN-25C | Recombinant Cynomolgus MSLN Protein, Fc tagged | +Inquiry |
MSLN-5659H | Recombinant Human MSLN Protein, GST-tagged | +Inquiry |
MSLN-5745M | Recombinant Mouse MSLN Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
MSLN-1316HCL | Recombinant Human MSLN cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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