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Recombinant Mouse MSLN Protein (298-600 aa), His-SUMO-tagged

Cat.No. : MSLN-669M
Product Overview : Recombinant Mouse MSLN Protein (298-600 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Protein Description: Partial.
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  • Gene Information
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Description : Mbrane-anchored forms may play a role in cellular adhesion.
Source : E. coli
Species : Mouse
Tag : His-SUMO
Form : Tris-based buffer, 50% glycerol
Molecular Mass : 50.1 kDa
Protein length : 298-600 aa
AA Sequence : DAEQKACPPGKEPYKVDEDLIFYQN WELEACVDGTMLARQMDLVNEIPFT YEQLSIFKHKLDKTYPQGYPESLIQ QLGHFFRYVSPEDIHQWNVTSPDTV KTLLKVSKGQKMNAQAIALVACYLR GGGQLDEDMVKALGDIPLSYLCDFS PQDLHSVPSSVMWLVGPQDLDKCSQ RHLGLLYQKACSAFQNVSGLEYFEK IKTFLGGASVKDLRALSQHNVSMDI ATFKRLQVDSLVGLSVAEVQKLLGP NIVDLKTEEDKSPVRDWLFRQHQKD LDRLGLGLQGGIPNGYLVLDFNVRE AFS
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with concentration instruction is sent along with the products.
Gene Name : Msln mesothelin [ Mus musculus ]
Official Symbol : MSLN
Synonyms : MSLN; mesothelin; MPF;
Gene ID : 56047
mRNA Refseq : NM_018857
Protein Refseq : NP_061345
UniProt ID : Q61468

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What is the primary role of MSLN in normal tissues? 12/07/2022

MSLN is normally expressed in mesothelial cells, playing a role in cell adhesion.

How is MSLN expression altered in cancerous cells? 03/19/2022

In cancer, MSLN expression is significantly upregulated.

In which types of cancer is MSLN overexpressed? 03/28/2021

MSLN is overexpressed in mesothelioma, ovarian, and pancreatic cancers.

Are there any therapeutic strategies targeting MSLN in cancer treatment? 02/25/2020

Therapies targeting MSLN include antibody-drug conjugates and CAR-T cell therapies.

How can MSLN levels be detected and measured in clinical settings? 10/07/2019

MSLN levels can be assessed through immunohistochemistry and serum biomarker tests.

What is the prognostic significance of MSLN overexpression in cancer patients? 11/23/2018

MSLN overexpression is often associated with poor prognosis in cancer patients.

How does MSLN contribute to cancer progression and metastasis? 11/07/2018

MSLN promotes tumor cell proliferation, invasion, and resistance to apoptosis.

Customer Reviews (3)

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Reviews
05/22/2022

    Very satisfied, great product.

    03/06/2022

      Product is high-quality.

      09/30/2021

        Excellent for experiments, reliable.

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