Recombinant Human MYD88 Protein, GST-tagged

• Cat.No.: MYD88-5796H
• Product Overview: Human MYD88 full-length ORF ( AAH13589.1, 1 a.a. - 296 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 58.3 kDa
• AA Sequence: MAAGGPGAGSAAPVSSTSSLPLAAL NMRVRRRLSLFLNVRTQVAADWTAL AEEMDFEYLEIRQLETQADPTGRLL DAWQGRPGASVGRLLELLTKLGRDD VLLELGPSIEEDCQKYILKQQQEEA EKPLQVAAVDSSVPRTAELAGITTL DDPLGHMPERFDAFICYCPSDIQFV QEMIRQLEQTNYRLKLCVSDRDVLP GTCVWSIASELIEKRCRRMVVVVSD DYLQSKECDFQTKFALSLSPGAHQK RLIPIKYKAMKKEFPSILRSITVCD YTNPCTKSWFWTRLAKALSLP
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: MYD88 myeloid differentiation primary response gene (88) [ Homo sapiens ]
• Official Symbol: MYD88
• Synonyms: MYD88; myeloid differentiation primary response gene (88); myeloid differentiation primary response protein MyD88; MYD88D
• Gene ID: 4615
• mRNA Refseq: NM_001172566
• Protein Refseq: NP_001166037
• MIM: 602170
• UniProt ID: Q99836