Recombinant Human MYD88 Protein, GST-tagged

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Recombinant Human MYD88 Protein, GST-tagged

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Cat.No. : MYD88-5796H
Product Overview : Human MYD88 full-length ORF ( AAH13589.1, 1 a.a. - 296 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 58.3 kDa
AA Sequence : MAAGGPGAGS AAPVSSTSSL PLAALNMRVR RRLSLFLNVR TQVAADWTAL AEEMDFEYLE IRQLETQADP TGRLLDAWQG RPGASVGRLL ELLTKLGRDD VLLELGPSIE EDCQKYILKQ QQEEAEKPLQ VAAVDSSVPR TAELAGITTL DDPLGHMPER FDAFICYCPS DIQFVQEMIR QLEQTNYRLK LCVSDRDVLP GTCVWSIASE LIEKRCRRMV VVVSDDYLQS KECDFQTKFA LSLSPGAHQK RLIPIKYKAM KKEFPSILRS ITVCDYTNPC TKSWFWTRLA KALSLP
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing: :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : MYD88 myeloid differentiation primary response gene (88) [ Homo sapiens ]
Official Symbol : MYD88
Synonyms : MYD88; myeloid differentiation primary response gene (88); myeloid differentiation primary response protein MyD88; MYD88D;
Gene ID : 4615
mRNA Refseq : NM_001172566
Protein Refseq : NP_001166037
MIM : 602170
UniProt ID : Q99836

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