Recombinant Human NPHS2 Protein, GST-tagged

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Recombinant Human NPHS2 Protein, GST-tagged

NPHS2 Related Products

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Cat.No. : NPHS2-6032H
Product Overview : Human NPHS2 full-length ORF ( AAH29141.1, 1 a.a. - 315 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined.
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 60.8 kDa
AA Sequence : MERRARSSSR ESRGRGGRTP HKENKRAKAE RSGGGRGRQE AGPEPSGSGR AGTPGEPRAP AATVVDVDEV RGSGEEGTEV VALLESERPE EGTKSSGLGA CEWLLVLISL LFIIMTFPFS IWFCVKVVQE YERVIIFRLG HLLPGRAKGP GLFFFLPCLD TYHKVDLRLQ TLEIPFHEVA LDSVTCIWGI KVERIEIKDV RLPAGLQHSL AVEAEAQRQA KVRMIAAEAE KAASESLRMA AEILSGTPAA VQLRYLHTLQ SLSTEKPSTV VLPLPFDLLN CLSSPSNRTQ GSLPFPSPSK PVEPLNPKKK DSPML
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing: :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : NPHS2 podocin [ Homo sapiens ]
Official Symbol : NPHS2
Synonyms : NPHS2; podocin; PDCN; SRN1;
Gene ID : 50521

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