Recombinant Human NPHS2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: NPHS2-2142H
• Product Overview: NPHS2 MS Standard C13 and N15-labeled recombinant protein (NP_055440) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a protein that plays a role in the regulation of glomerular permeability. Mutations in this gene cause steroid-resistant nephrotic syndrome. Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 42 kDa
• AA Sequence: MERRARSSSRESRGRGGRTPHKENK RAKAERSGGGRGRQEAGPEPSGSGR AGTPGEPRAPAATVVDVDEVRGSGE EGTEVVALLESERPEEGTKSSGLGA CEWLLVLISLLFIIMTFPFSIWFCV KVVQEYERVIIFRLGHLLPGRAKGP GLFFFLPCLDTYHKVDLRLQTLEIP FHEIVTKDMFIMEIDAICYYRMENA SLLLSSLAHVSKAVQFLVQTTMKRL LAHRSLTEILLERKSIAQDAKVALD SVTCIWGIKVERIEIKDVRLPAGLQ HSLAVEAEAQRQAKVRMIAAEAEKA ASESLRMAAEILSGTPAAVQLRYLH TLQSLSTEKPSTVVLPLPFDLLNCL SSPSNRTQGSLPFPSPSKPVEPLNP KKKDSPMLTRTRPLEQKLISEEDLA ANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: NPHS2 podocin [ Homo sapiens (human) ]
• Official Symbol: NPHS2
• Synonyms: NPHS2; NPHS2 stomatin family member, podocin; PDCN; SRN1; podocin; NPHS2, podocin; nephrosis 2, idiopathic, steroid-resistant (podocin)
• Gene ID: 7827
• mRNA Refseq: NM_014625
• Protein Refseq: NP_055440
• MIM: 604766
• UniProt ID: Q9NP85