Recombinant Human P2RX7 Protein, GST-tagged

Cat.No. : P2RX7-390H
Product Overview : Human P2RX7 full-length ORF ( AAH11913.1, 1 a.a. - 595 a.a.) recombinant protein with GST-tag at N-terminal was expressed in Wheat Germ.
  • Specification
  • Gene Information
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Description : The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria.
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 94.9 kDa
Protein length : 1-595
AA Sequence : MPACCSCSDVFQYETNKVTRIQSMN YGTIKWFFHVIIFSYVCFALVSDKL YQRKEPVISSVHTKVKGIAEVKEEI VENGVKKLVHSVFDTADYTFPLQGN SFFVMTNFLKTEGQEQRLCPEYPTR RTLCSSDRGCKKGWMDPQSKGIQTG RCVVHEGNQKTCEVSAWCPIEAVEE APRPALLNSAENFTVLIKNNIDFPG HNYTTRNILPGLNITCTFHKTQNPQ CPIFRLGDIFRETGDNFSDVAIQGG IMGIEIYWDCNLDRWFHHCHPKYSF RRLDDKTTNVSLYPGYNFRYAKYYK ENNVEKRTLIKVFGIRFDILVFGTG GKFDIIQLVVYIGSTLSYFGLAAVF IDFLIDTYSSNCCRSHIYPWCKCCQ PCVVNEYYYRKKCESIVEPKPTLKY VSFVDESHIRMVNQQLLGRSLQDVK GQEVPRPAMDFTDLSRLPLALHDTP PIPGQPEEIQLLRKEATPRSRDSPV WCQCGSCLPSQLPESHRCLEELCCR KKPGACITTSELFRKLVLSRHVLQF LLLYQEPLLALDVDSTNSRLRHCAY RCYATWRFGSQDMADFAILPSCCRW RIRKEFPKSEGQYSGFKSPY
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.
Gene Name : P2RX7 purinergic receptor P2X 7 [ Homo sapiens (human) ]
Official Symbol : P2RX7
Synonyms : P2RX7; purinergic receptor P2X 7; P2X7; P2X purinoceptor 7; ATP receptor; P2X7 receptor; P2Z receptor; purinergic receptor P2X, ligand gated ion channel, 7; purinergic receptor P2X7 variant A; purnergic receptor P2X 7
Gene ID : 5027
mRNA Refseq : NM_002562
Protein Refseq : NP_002553
MIM : 602566
UniProt ID : Q99572

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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