Recombinant Human PARP1 Protein, FLAG/Avi-tagged
Cat.No. : | PARP1-431H |
Product Overview : | Human PARP1 (NM_001618), full length with N-terminal FLAG-Avi-tag™,expressed in a Baculovirus infected Sf9 cell expression system. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. |
Source : | Insect Cell |
Species : | Human |
Tag : | FLAG/Avi |
Form : | Aqueous buffer solution |
Molecular Mass : | 117 kDa |
Applications : | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
Stability : | At least 6 months at -80 centigrade. |
Storage Buffer : | 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, 20% glycerol, 0.2mM TCEP, 80 μg/ml FLAG peptide |
Shipping : | -80 centigrade |
Warning : | Avoid freeze/thaw cycles. Storing diluted enzyme is not recommended, if necessary, use carrier protein (BSA 0.1 – 0.5%). |
Gene Name : | PARP1 poly(ADP-ribose) polymerase 1 [ Homo sapiens (human) ] |
Official Symbol : | PARP1 |
Synonyms : | PARP1; poly(ADP-ribose) polymerase 1; PARP; PPOL; ADPRT; ARTD1; ADPRT1; PARP-1; ADPRT 1; pADPRT-1; poly [ADP-ribose] polymerase 1; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase); ADP-ribosyltransferase NAD(+); ADP-ribosyltransferase diphtheria toxin-like 1; DNA ADP-ribosyltransferase PARP1; NAD(+) ADP-ribosyltransferase 1; poly (ADP-ribose) polymerase family, member 1; poly(ADP-ribose) synthetase; poly(ADP-ribosyl)transferase; poly[ADP-ribose] synthase 1; protein poly-ADP-ribosyltransferase PARP1; EC 2.4.2.30 |
Gene ID : | 142 |
mRNA Refseq : | NM_001618 |
Protein Refseq : | NP_001609 |
MIM : | 173870 |
UniProt ID : | P09874 |
Products Types
◆ Recombinant Protein | ||
PARP1-2615H | Recombinant Human PARP1 protein(61-370 aa), C-His-tagged | +Inquiry |
PARP1-59H | Recombinant Human PARP1 Protein | +Inquiry |
PARP1-075H | Recombinant Human PARP1 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
PARP1-1531H | Recombinant Human PARP1 Protein, His-tagged | +Inquiry |
Parp1-548M | Recombinant Mouse Parp1 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
PARP1-514MCL | Recombinant Mouse PARP1 cell lysate | +Inquiry |
PARP1-710HCL | Recombinant Human PARP1 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1792 | PARP1 Chemiluminescent Assay Kit | +Inquiry |
Kit-1793 | PARP1 Chemiluminescent Assay Kit (384-well) | +Inquiry |
Kit-1794 | PARP1 Colorimetric Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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